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Evidence based medicine (EBM) consists of identifying a clinical problem or question, doing a focused search in the literature for relevant studies, choosing the most pertinent studies, and critically evaluating them for guidance as to the right answer to the initial clinical question. This is a volume that is dependent upon evidence-based data to support the difficult decisions made in the course of treating critically ill patients in the ICU. The authors were tasked with developing their chapter themes by structuring the questions to be asked according to the PICO (Patients of interest, the Intervention that was applied, Comparator patients with similar conditions but treated differently, and Outcomes of interest) model.
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