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Sarcoidosis is a chronic, systemic inflammatory disorder characterised by the presence of epithelioid non-caseating granulomata in the affected organs. The lungs are affected in about 90% of the cases, and pulmonary disease accounts for most of the morbidity and mortality associated with sarcoidosis. Virtually every organ of the body can be affected like the liver, skin, eye etc. The features of granulomata are not specific for sarcoidosis and other conditions known to cause granulomata must be excluded. These conditions include mycobacterial and fungal infections, environmental agents such as beryllium, malignancy and others.
References and Further Reading
- Statement on sarcoidosis. Joint statement of the American Thoracic Society (ATS), the European Respiratory Society (ERS) and the World Association of Sarcoidosis and Other Granulomatous Disorders (WASOG) adopted by the ATS Board of Directors and by the ERS Executive Committee, February 1999. Am J Respir Crit Care Med. 1999;160(2):736–55.Google Scholar