Osteoporosis (OP) is a generalised metabolic bone disease characterised by insufficient formation or increased resorption of bone matrix, resulting in decreased bone mass and susceptibility to bone fractures. OP has a variety of possible causes and consequently manifests in a number of different forms, but the result is the same which is bone fracture. The basic distinction is between generalised or diffuse OP involving the vertebral bones, the femoral neck and wrists with different type of fractures. On the other hand, there is a localised OP to a simple region or bone which is called regional OP. This type of OP, particularly if accompanied by pain, frequently can masquerade as arthritis.