Advertisement

Feeding Problems in Congenital Hyperinsulinism

  • Caroline Hall
  • Indraneel Banerjee
Chapter
Part of the Contemporary Endocrinology book series (COE)

Abstract

Feeding is an essential activity for all children, providing nutrition and maintaining normal glucose levels. In children with congenital hyperinsulinism (HI), feeding difficulties are common, and a significant proportion of infants with HI require feeding support, complicating medical management. It is important to recognize potential causes and mechanisms contributing to feeding problems and address these through sustained multidisciplinary input to improve the long-term well-being of children with HI.

Keywords

Feeding Feeding problems Hyperinsulinism Glucose Hypoglycemia Congenital hyperinsulinism Hyperinsulinemic hypoglycemia Tube feeding Oral feeding 

References

  1. 1.
    Arvedson JC. Swallowing and feeding in infants and young children in Goyal & Shaker GI Motility Online. 2006.  https://doi.org/10.1038/gimo17 http://www.nature.com/gimo. Accessed 13 Mar 2017.
  2. 2.
    Entwistle FM. The evidence and rationale for the UNICEF UK Baby Friendly Initiative standards. 2013; UNICEF UK.Google Scholar
  3. 3.
    Gerozissis K. Brain insulin and feeding: a bi-directional communication. Eur J Pharmacol. 2004;490(1–3):59–70.CrossRefGoogle Scholar
  4. 4.
    Jadcherla S. Dysphagia in the high-risk infant: potential factors and mechanisms. Am J Clin Nutr. 2016;103(2):622S–8S.  https://doi.org/10.3945/ajcn.115.110106. Epub 2016 Jan 20.CrossRefPubMedPubMedCentralGoogle Scholar
  5. 5.
    Lau C. Development of infant oral feeding skills: what do we know? Am J Clin Nutr. 2016;103(2):616S–21S.  https://doi.org/10.3945/ajcn.115.109603. Epub 2016 Jan 20. Review. PMID: 26791183.CrossRefPubMedPubMedCentralGoogle Scholar
  6. 6.
    Shaker CS. Cue-based feeding in the NICU: using the infant’s communication as a guide. Neonatal Network. 2013;32(6):404–8., cited in Watson J, McGuire W. Responsive versus scheduled feeding for preterm infants. Cochrane Database of Systematic Reviews 2016, Issue 8. Art. No.: CD005255.  https://doi.org/10.1002/14651858.CD005255.pub5.CrossRefPubMedGoogle Scholar
  7. 7.
    Al-Shanafey S, Alkhudhur H. Food aversion among patients with persistent hyperinsulinemic hypoglycemia of infancy. J Pediatr Surg. 2012;47(5):895–7.  https://doi.org/10.1016/j.jpedsurg.2012.03.002.CrossRefPubMedGoogle Scholar
  8. 8.
    Belgardt BF, Brüning JC. CNS leptin and insulin action in the control of energy homeostasis. Ann N Y Acad Sci. 2010;1212:97–113.CrossRefGoogle Scholar
  9. 9.
    Browne JV, Ross ES. Feeding outcomes in preterm infants after discharge from the neonatal intensive care unit (NICU): a systematic review. Newborn Infant Nurs Rev. 2013;13:87–93.CrossRefGoogle Scholar
  10. 10.
    Ross ES, Philbin MK. SOFFI: an evidence-based method for quality bottle-feedings of preterm, ill and fragile infants. J Perinat Neonatal Nurs. 2011;25(4):349–59.  https://doi.org/10.1097/JPN.0b013e318234ac7a.CrossRefPubMedPubMedCentralGoogle Scholar
  11. 11.
    Rudolph CD, Link DT. Feeding disorders in infants and children. Pediatr Clin N Am. 2002;49(1):97–112. vi.CrossRefGoogle Scholar
  12. 12.
    Stevenson RD, Allaire JH. The development of normal feeding and swallowing. Paediatr Clin N Am. 1991;38:1439–53. cited in Jones, E, King, C. Feeding and Nutrition in the Preterm Infant. Elsevier. 2005.CrossRefGoogle Scholar
  13. 13.
    Watson J, McGuire W. Responsive versus scheduled feeding for preterm infants. In: Cochrane database of systematic reviews. 2016, Issue 8. Art. No.: CD005255.  https://doi.org/10.1002/14651858.CD005255.pub5. http://onlinelibrary.wiley.com. Accessed 17 Mar 2017.
  14. 14.
    Arnoux JB, Verkarre V, Saint-Martin C, Montravers F, Brassier A, Valayannopoulos V, Brunelle F, Fournet JC, Robert JJ, Aigrain Y, Bellanné-Chantelot C, de Lonlay P. Congenital hyperinsulinism: current trends in diagnosis and therapy. Orphanet J Rare Dis. 2011;6:63.  https://doi.org/10.1186/1750-1172-6-63.CrossRefPubMedPubMedCentralGoogle Scholar
  15. 15.
    Avatapalle B, Padidela R, Randell T, Banerjee I. Drug-induced hepatitis following use of octreotide for long-term treatment of congenital hyperinsulinism. BMJ Case Rep. 2012;2012. pii: bcr2012006271.  https://doi.org/10.1136/bcr-2012-006271.Google Scholar
  16. 16.
    Banerjee I, Skae M, Flanagan SE, Rigby L, Patel L, Didi M, Blair J, Ehtisham S, Ellard S, Cosgrove KE, Dunne MJ, Clayton PE. The contribution of rapid KATP channel gene mutation analysis to the clinical management of children with congenital hyperinsulinism. Eur J Endocrinol. 2011;164(5):733–40.  https://doi.org/10.1530/EJE-10-1136. Epub 2011 Mar 4.CrossRefPubMedGoogle Scholar
  17. 17.
    Banerjee I, Forsythe L, Skae M, Avatapalle HB, Rigby L, Bowden LE, Craigie R, Padidela R, Ehtisham S, Patel L, Cosgrove KE, Dunne MJ, Clayton PE. Feeding problems are persistent in children with severe congenital hyperinsulinism. Front Endocrinol (Lausanne). 2016;7:8.  https://doi.org/10.3389/fendo.2016.00008. eCollection 2016.CrossRefGoogle Scholar
  18. 18.
    Beker F, Opie G, Noble E, Jiang Y, Bloomfield FH. Smell and taste to improve nutrition in very preterm infants: a randomized controlled pilot trial. Neonatology. 2017;111(3):260–6.  https://doi.org/10.1159/000450883. Epub 2016 Dec 1.CrossRefPubMedGoogle Scholar
  19. 19.
    Berlin KS, Lobato DJ, Pinkos B, Cerezo CS, LeLeiko NS. Patterns of medical and developmental comorbidities among children presenting with feeding problems: a latent class analysis. J Dev Behav Pediatr. 2011;32:41–7.CrossRefGoogle Scholar
  20. 20.
    Borra C, Iacovou M, Sevilla A. New evidence on breastfeeding and postpartum depression: the importance of understanding women’s intentions. Matern Child Health J. 2015;19(4):897–0.CrossRefGoogle Scholar
  21. 21.
    Fox SE, Levitt P, Nelson CA. How the timing and quality of early experiences influence the development of brain architecture. Child Dev. 2010;81(1):28–40.CrossRefGoogle Scholar
  22. 22.
    Friciu M, Zaraa S, Roullin VG, Leclair G. Stability of diazoxide in extemporaneously compounded oral suspensions. PLoS ONE. 2016;11(10):e0164577.  https://doi.org/10.1371/journal.pone.0164577.CrossRefGoogle Scholar
  23. 23.
    Goldfield EC, Perez J, Engstler K. Neonatal feeding behavior as a complex dynamical system. Semin Speech Lang. 2017;38(2):77–86.  https://doi.org/10.1055/s-0037-1599105. Epub 2017 Mar 21.CrossRefPubMedGoogle Scholar
  24. 24.
    Havrankova J, Brownstein M, Roth J. Insulin and insulin receptors in rodent brain. Diabetologia. 1981;20(Suppl):268–73.CrossRefGoogle Scholar
  25. 25.
    Jadcherla SR, Stoner E, Gupta A, Bates DG, Fernandez S, Di Lorenzo C, Linscheid T. Evaluation and management of neonatal dysphagia: impact of pharyngoesophageal motility studies and multidisciplinary feeding strategy. J Pediatr Gastroenterol Nutr. 2009;48(2):186–92.  https://doi.org/10.1097/MPG.0b013e3181752ce7.CrossRefPubMedPubMedCentralGoogle Scholar
  26. 26.
    Jung JS, Chang HJ, Kwon J-Y. Overall profile of a paediatric multidisciplinary feeding clinic. Ann Rehabil Med. 2016;40(4):692–701.CrossRefGoogle Scholar
  27. 27.
    Malik S, McGlone F, Bedrossian D, Dagher A. Ghrelin modulates brain activity in areas that control appetitive behavior. Cell Metab. 2008;7(5):400–9.  https://doi.org/10.1016/j.cmet.2008.03.007.CrossRefPubMedGoogle Scholar
  28. 28.
    Manno CJ, Fox C, Eicher PS, Kerwin ME. Early oral-motor interventions for paediatric feeding problems: what, when and how. Jeibi. 2005;2(3):145–59.Google Scholar
  29. 29.
    McKean EB, Kasparian NA, Batra S, Sholler GF, Winlaw DS, Dalby-Payne J. Feeding difficulties in neonates following cardiac surgery: determinants of prolonged feeding-tube use. Cardiol Young. 2017;23:1–9.  https://doi.org/10.1017/S1047951116002845. (Epub ahead of print).CrossRefGoogle Scholar
  30. 30.
    Meek CL, Lewis HB, Reimann F, Gribble FM, Park AJ. The effect of bariatric surgery on gastrointestinal and pancreatic peptide hormones. Peptides. 2016;77:28–37.  https://doi.org/10.1016/j.peptides.2015.08.013. Epub 2015 Sep 5.CrossRefPubMedGoogle Scholar
  31. 31.
    Merhar SL, Pentiuk SP, Mukkada VA, Meinzen-Derr J, Kaul A, Butler DR. A retrospective review of cyproheptadine for feeding intolerance in children less than three years of age: effects and side effects. Acta Paediatr. 2016;105(8):967–70.  https://doi.org/10.1111/apa.13477. Epub 2016 June 10.CrossRefPubMedGoogle Scholar
  32. 32.
    Norris FJ, Larkin MS, William CM, Hampton SM, Morgan JB. Factors affecting the introduction of complementary foods in the preterm infant. Eur J Clin Nutr. 2002;56:448–84.CrossRefGoogle Scholar
  33. 33.
    Quitadamo P, Thapar N, Staiano A, Borrelli O. Gastrointestinal and nutritional problems in neurologically impaired children. Eur J Paediatr Neurol. 2016;20(6):810–5.  https://doi.org/10.1016/j.ejpn.2016.05.019. Epub 2016 June 11.CrossRefPubMedGoogle Scholar
  34. 34.
    Salomon-Estebanez M, Flanagan SE, Ellard S, Rigby L, Bowden L, Mohamed Z, Nicholson J, Skae M, Hall C, Craigie R, Padidela R, Murphy N, Randell T, Cosgrove KE, Dunne MJ, Banerjee I. Conservatively treated Congenital Hyperinsulinism (CHI) due to K-ATP channel gene mutations: reducing severity over time. Orphanet J Rare Dis. 2016;11(1):163.CrossRefGoogle Scholar
  35. 35.
    Wellhauser L, Chalmers JA, Belsham DD. Nitric oxide exerts basal and insulin-dependent anorexigenic actions in POMC hypothalamic neurons. Mol Endocrinol. 2016;30(4):402–16.  https://doi.org/10.1210/me.2015-1275. Epub 2016 Mar 1.PMID: 26930171.CrossRefPubMedPubMedCentralGoogle Scholar
  36. 36.
    Zanchi D, Depoorter A, Egloff L, Haller S, Mählmann L, Lang UE, Drewe J, Beglinger C, Schmidt A, Borgwardt S. The impact of gut hormones on the neural circuit of appetite and satiety: a systematic review. Neurosci Biobehav Rev. 2017;80:457–75.  https://doi.org/10.1016/j.neubiorev.2017.06.013. (Epub ahead of print).CrossRefPubMedGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Caroline Hall
    • 1
  • Indraneel Banerjee
    • 1
  1. 1.Department of Paediatric EndocrinologyRoyal Manchester Children’s HospitalManchesterUK

Personalised recommendations