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Keratin Production and Its Applications: Current and Future Perspective

  • Anshuman Shah
  • Shaily Tyagi
  • Ram Naresh Bharagava
  • Dalel Belhaj
  • Ashok Kumar
  • Gaurav Saxena
  • Ganesh Dattatraya Saratale
  • Sikandar I. MullaEmail author
Chapter
Part of the Springer Series on Polymer and Composite Materials book series (SSPCM)

Abstract

Keratin is a global class of biological material, which represents a group of cysteine-rich filament-forming proteins. They serve as a shielding layer for the epidermal appendages like nails, claws, beak, hair, wool, horns, and feathers. These proteins are further subdivided into two different class based on their secondary structure: α-keratin and β-keratin. Keratin is insoluble in hot or cold water; this unique property helps to prevent their digestion by proteolytic enzymes. Additionally, their complex hierarchical-like filament-matrix structure at nanoscale and the polypeptide chains create a robust wall for protection against heat stress, pathogen invasions (particularly through skin), mechanical damage, etc. In this review, we are trying to attempt a linear focus in the direction of structure, function, extraction of keratin, and its industrial applications.

Keywords

Keratin Keratin structure Keratin production Keratin application 

Notes

Acknowledgements

The authors are very thankful to the Mr. Chaitanya Sharma and Ms. Arshia Gupta for their valuable suggestions during designing of 3D structure of keratin protein.

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Anshuman Shah
    • 1
  • Shaily Tyagi
    • 1
  • Ram Naresh Bharagava
    • 2
  • Dalel Belhaj
    • 3
  • Ashok Kumar
    • 4
  • Gaurav Saxena
    • 2
  • Ganesh Dattatraya Saratale
    • 5
  • Sikandar I. Mulla
    • 6
    • 7
    Email author
  1. 1.ICAR-National Research Centre on Plant BiotechnologyNew DelhiIndia
  2. 2.Laboratory of Bioremediation and Metagenomics Research (LBMR), Department of Environmental Microbiology (DEM)Babasaheb Bhimrao Ambedkar University (A Central University)LucknowIndia
  3. 3.Laboratory of Biodiversity and Aquatic Ecosystems Ecology and Planktonology, Department of Life SciencesUniversity of Sfax-Tunisia, FSSSfaxTunisia
  4. 4.Department of Biotechnology and BioinformaticsJaypee University of Information TechnologyWaknaghat, SolanIndia
  5. 5.Department of Food Science and BiotechnologyDongguk University-SeoulGoyang-SiRepublic of Korea
  6. 6.Key Laboratory of Urban Pollutant Conversion, Institute of Urban EnvironmentChinese Academy of SciencesXiamenChina
  7. 7.Department of BiochemistryKarnatak UniversityDharwadIndia

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