Adolescent Testicular Sperm Retrieval
A 16-year-old male presented to a community hospital with 2 weeks of decreased urinary flow, which ultimately progressed to urinary retention. An indwelling Foley catheter was placed, and initial evaluation revealed no laboratory abnormalities. Magnetic resonance imaging (MRI) of the abdomen and pelvis demonstrated an enhancing mass within the anterior prostate measuring 4.2 × 5.2 × 4.6 cm. A right femoral head lesion was also noted. Percutaneous biopsy of the prostatic lesion confirmed a diagnosis of embryonal rhabdomyosarcoma, and further staging evaluation revealed Stage 4, high-risk disease. The patient was transferred to a tertiary-care pediatric hospital for treatment with the following chemotherapeutic regimen: vincristine, irinotecan, ifosfamide, etoposide, doxorubicin, cyclophosphamide, dactinomycin, and human IgG1 monoclonal antibody. The total cyclophosphamide equivalent dose (CED) for the planned treatment regimen was 16,290 mg/m2.
KeywordsOncofertility Adolescence Sperm retrieval Embryonal rhabdomyosarcoma Microdissection testicular sperm extraction (microTESE)
- 4.van Casteren NJ, Dohle GR, Romijn JC, de Muinck Keizer-Schrama SMPF, Weber RFA, van den Heuvel-Eibrink MM. Semen cryopreservation in pubertal boys before gonadotoxic treatment and the role of endocrinologic evaluation in predicting sperm yield. Fertil Steril. 2008;90(4):1119–25.CrossRefPubMedCentralGoogle Scholar
- 21.Chiba K, Tanaka M, Ishida T, Sumii K, Fukuda T, Okada K, et al. Mp07-18 the usage rate of semen cryopreservation before cancer treatment. J Urol. 2018;199(4):e94–5.Google Scholar