Fertility Preservation at an Advanced Reproductive Age: When Hope and Reality Collide

  • Jacquelyn Shaw
  • Kara N. GoldmanEmail author


A 41-year-old G2P0020 female with a history of endometriosis and newly diagnosed stage I estrogen receptor positive, progesterone receptor positive, human epidermal growth factor receptor 2 negative (ER+/PR+/HER2−) breast cancer presented to discuss fertility preservation. The patient was diagnosed with breast cancer 3 months prior to presentation and had undergone a bilateral mastectomy with concurrent reconstruction with tissue expanders. BRCA testing was negative. Her treatment plan included a 10-year tamoxifen course but no requirement for chemotherapy. Her medical oncologist was willing to delay therapy to allow for fertility preservation.


Oncofertility Fertility preservation Advanced reproductive age Embryo cryopreservation Preimplantation genetic testing for aneuploidy (PGT-A) 


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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of Obstetrics and GynecologyNorthwestern University, New York University Langone Medical CenterNew YorkUSA
  2. 2.Department of Obstetrics and GynecologyNew York University Langone Medical CenterNew YorkUSA
  3. 3.Northwestern University Feinberg School of MedicineChicagoUSA

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