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Designing Randomized Clinical Trials in Dermatologic Surgery

  • Murad AlamEmail author
Chapter

Abstract

There are many ways to better understand how to diagnose and treat our patients. An unusually powerful tool is the randomized controlled trial (RCT). The first well-reported RCT assessed utility of streptomycin for the treatment of tuberculosis in 1948 (Williams, How to critically appraise a randomized controlled trial. In: Williams H, Bigby M, Herxheimer A, Naldi L, Rzany B, Dellavale R, Ran Y, Furue E (eds) Evidence-based dermatology, 3rd edn. Wiley, New York, pp 39–45, 2014). Although a relatively newcomer to the scientific toolbox, the blinded RCT is now widely acknowledged as the key building block that underpins high-level medical evidence.

Keywords

Outcome Patient RCT Surgery Trial Intervention Core 

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Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Department of DermatologyNorthwestern Medicine, Feinberg School of MedicineChicagoUSA

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