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A Temporal Estimate of Integrated Information for Intracranial Functional Connectivity

  • Xerxes D. ArsiwallaEmail author
  • Daniel Pacheco
  • Alessandro Principe
  • Rodrigo Rocamora
  • Paul Verschure
Conference paper
Part of the Lecture Notes in Computer Science book series (LNCS, volume 11140)

Abstract

A major challenge in computational and systems neuroscience concerns the quantification of information processing at various scales of the brain’s anatomy. In particular, using human intracranial recordings, the question we ask in this paper is: How can we estimate the informational complexity of the brain given the complex temporal nature of its dynamics? To address this we work with a recent formulation of network integrated information that is based on the Kullback-Leibler divergence between the multivariate distribution on the set of network states versus the corresponding factorized distribution over its parts. In this work, we extend this formulation for temporal networks and then apply it to human brain data obtained from intracranial recordings in epilepsy patients. Our findings show that compared to random re-wirings of the data, functional connectivity networks, constructed from human brain data, score consistently higher in the above measure of integrated information. This work suggests that temporal integrated information may indeed be a good starting point as a future measure of cognitive complexity.

Keywords

Computational neuroscience Brain networks Complexity measures Functional connectivity 

Notes

Acknowledgments

This work is supported by the European Research Council’s CDAC project: “The Role of Consciousness in Adaptive Behavior: A Combined Empirical, Computational and Robot based Approach”, (ERC-2013- ADG 341196).

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Copyright information

© Springer Nature Switzerland AG 2018

Authors and Affiliations

  • Xerxes D. Arsiwalla
    • 1
    • 2
    • 4
    Email author
  • Daniel Pacheco
    • 1
    • 2
    • 4
  • Alessandro Principe
    • 3
  • Rodrigo Rocamora
    • 3
  • Paul Verschure
    • 2
    • 4
    • 5
  1. 1.Universitat Pompeu FabraBarcelonaSpain
  2. 2.Institute for BioEngineering of CataloniaBarcelonaSpain
  3. 3.Hospital del MarBarcelonaSpain
  4. 4.Barcelona Institue of Science and TechnologyBarcelonaSpain
  5. 5.Institució Catalana de Recerca i Estudis Avançats (ICREA)BarcelonaSpain

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