Intensive Care Unit Model of Modern Hospital: Genomically Oriented and Biology-Based
Despite modern advances in technology and our understanding of biology, current critical care can be characterized as imprecise. Although evidence-based clinical outcome research can serve as a “guide” to best practices in critical care, emerging technology in bioinformatics and the genetic basis of disease must service as a platform upon which critical care treatment plans can be tailored to the individual patient. Enthusiasm and progress in genomically oriented medicine should be modeled after early success observed in other areas of medicine such as oncology, psychiatry, pulmonology, and cardiology where the genetic basis of disease has led to precise algorithms for treatment based upon individualized patient biology as opposed to disease pathophysiology.
KeywordsCritical care Genomics Biology Clinical trials Precision medicine
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