Pharmacy Implications

  • Stacey AlbuquerqueEmail author


The immunocompromised patient may be admitted to the ICU as a consequence of a new diagnosis, treatment-related toxicity, or disease progression. The pharmacologic management of the critically ill immunocompromised child in the pediatric intensive care unit (PICU) brings forth a unique set of challenges as these patients are often prone to medication toxicity due to their organ compromise and increased potential for the development of drug interactions due to the amount of medications that may be utilized to treat evolving conditions. In addition to understanding the immunologic or oncologic processes of these patients, knowledge and understanding drug disposition and drug interactions are necessary to maximize efficacy of treatment and minimize medication-induced toxicity where possible.


Immunocompromised Pharmacology drug disposition Drug interactions Toxicity 


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Copyright information

© Springer International Publishing 2019

Authors and Affiliations

  1. 1.Boston Children’s Pharmacy DepartmentDana Farber/Boston Children’s Cancer and Blood Disorders CenterBostonUSA

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