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Endoscopic Detection and Analysis of Mucosal Neoplastic Lesions: Enhanced Imaging and Tumor Morphology

  • Frieder Berr
  • Thierry Ponchon
  • Toshio UraokaEmail author
Chapter

Abstract

Endoscopic imaging techniques aim for detection of small (even minute) neoplasias and analysis of macroscopic type, microsurface structure, and capillary architecture. Magnifying image-enhanced endoscopy displays surface and capillary architecture of normal and neoplastic mucosa and allows highly accurate endoscopic diagnosis of margins, malignant transformation, and lack of deep submucosal invasion of early mucosal neoplasias, which is fundamental for curative endoscopic resection. This chapter introduces techniques and diagnostic analysis of image-enhanced endoscopy.

Keywords

Endoscopic techniques, diagnostic Chromoendoscopy Narrow band imaging Image-enhanced endoscopy Mucosal neoplasias, Paris classification Microvessel pattern Microsurface pattern 

Notes

Acknowledgments

The contribution of cases or images by Dr. Hans-Peter Allgaier, Freiburg, Germany; Dr. Gerhard Kleber, Aalen, Germany; Dr. Tsuneo Oyama, Saku Central Hospital, Nagano, Japan; and Dr. Daniel Neureiter, University Institute of Pathology, Salzburg, Austria, is gratefully acknowledged.

References

  1. 1.
    Ferlay J, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer. 2015;136:E359–86.CrossRefGoogle Scholar
  2. 2.
    Inoue M, et al. Epidemiology of gastric cancer in Japan. Postgrad Med J. 2005;81:419–24.CrossRefGoogle Scholar
  3. 3.
    The Paris endoscopic classification of superficial neoplastic lesions: esophagus, stomach, and colon: November 30 to December 1, 2002. Gastrointest Endosc. 2003;58:S3–43.Google Scholar
  4. 4.
    George SM, et al. Classification of advanced colorectal carcinomas by tumor edge morphology: evidence for different pathogenesis and significance of polypoid and nonpolypoid tumors. Cancer. 2000;89:1901–9.CrossRefGoogle Scholar
  5. 5.
    Heresbach D, et al. Miss rate for colorectal neoplastic polyps: a prospective multicenter study of back-to-back video colonoscopies. Endoscopy. 2008;40:284–90.CrossRefGoogle Scholar
  6. 6.
    Yao K, et al. Development of an e-learning system for teaching endoscopists how to diagnose early gastric cancer: basic principles for improving early detection. Gastric Cancer. 2017;20(Suppl 1):S28–38.CrossRefGoogle Scholar
  7. 7.
    Kaltenbach T, et al. American Gastroenterological Association (AGA) Institute technology assessment on image-enhanced endoscopy. Gastroenterology. 2008;134:327–40.Google Scholar
  8. 8.
    Dohi O, et al. Diagnostic ability of magnifying endoscopy with blue laser imaging for early gastric cancer: a prospective study. Gastric Cancer. 2017;20:297–303.CrossRefGoogle Scholar
  9. 9.
    Kudo S, et al. Colonoscopic diagnosis and management of nonpolypoid early colorectal cancer. World J Surg. 2000;24:1081–90.CrossRefGoogle Scholar
  10. 10.
    Osawa H, et al. Present and future status of flexible spectral imaging color enhancement and blue laser imaging technology. Dig Endosc. 2014;26(Suppl 1):105–15.CrossRefGoogle Scholar
  11. 11.
    Uedo N, et al. Role of narrow band imaging for diagnosis of early-stage esophagogastric cancer: current consensus of experienced endoscopists in Asia-Pacific region. Dig Endosc. 2011;23(Suppl 1):58–71.CrossRefGoogle Scholar
  12. 12.
    Uraoka T, et al. Narrow-band imaging for improving colorectal adenoma detection: appropriate system function settings are required. Gut. 2009;58:604–5.CrossRefGoogle Scholar
  13. 13.
    Kudo S, et al. Pit pattern in colorectal neoplasia: endoscopic magnifying view. Endoscopy. 2001;33:367–73.CrossRefGoogle Scholar
  14. 14.
    Nakayoshi T, et al. Magnifying endoscopy combined with narrow band imaging system for early gastric cancer: correlation of vascular pattern with histopathology (including video). Endoscopy. 2004;36:1080–4.CrossRefGoogle Scholar
  15. 15.
    Sano Y, et al. Magnifying observation of microvascular architecture of colorectal lesions using a narrow-band imaging system. Dig Endosc. 2006;18:s44–51.CrossRefGoogle Scholar
  16. 16.
    Kodashima S, et al. Novel image-enhanced endoscopy with i-scan technology. World J Gastroenterol. 2010;16:1043–9.CrossRefGoogle Scholar
  17. 17.
    Yao K, et al. Development of an e-learning system for teaching endoscopists how to diagnose early gastric cancer: basic principles for improving early detection. Gastric Cancer. 2017;20:28–38.CrossRefGoogle Scholar
  18. 18.
    Muto M, et al. Magnifying endoscopy simple diagnostic algorithm for early gastric cancer (MESDA-G). Dig Endosc. 2016;28:379–93.CrossRefGoogle Scholar
  19. 19.
    Sano Y, et al. Narrow-band imaging (NBI) magnifying endoscopic classification of colorectal tumors proposed by the Japan NBI Expert Team. Dig Endosc. 2016;28:526–33.CrossRefGoogle Scholar
  20. 20.
    Update on the Paris classification of superficial neoplastic lesions in the digestive tract. Endoscopy. 2005;37:570–8.Google Scholar
  21. 21.
    Ishihara R, et al. Quantitative analysis of the color change after iodine staining for diagnosing esophageal high-grade intraepithelial neoplasia and invasive cancer. Gastrointest Endosc. 2009;69:213–8.CrossRefGoogle Scholar
  22. 22.
    Kondo H, et al. Sodium thiosulfate solution spray for relief of irritation caused by Lugol’s stain in chromoendoscopy. Gastrointest Endosc. 2001;53:199–202.CrossRefGoogle Scholar
  23. 23.
    Kawahara Y, et al. Novel chromoendoscopic method using an acetic acid-indigocarmine mixture for diagnostic accuracy in delineating the margin of early gastric cancers. Dig Endosc. 2009;21:14–9.CrossRefGoogle Scholar
  24. 24.
    Japanese Research Society for Gastric Cancer. Japanese classification of gastric carcinoma First English ed. Tokyo: Kanehara & Co., Ltd; 1995.Google Scholar
  25. 25.
    Everett SM, et al. Early gastric cancer in Europe. Gut. 1997;41:142–50.CrossRefGoogle Scholar
  26. 26.
    Rembacken BJ, et al. Flat and depressed colonic neoplasms: a prospective study of 1000 colonoscopies in the UK. Lancet. 2000;355:1211–4.CrossRefGoogle Scholar
  27. 27.
    Uraoka T, et al. Endoscopic indications for endoscopic mucosal resection of laterally spreading tumours in the colorectum. Gut. 2006;55:1592–7.CrossRefGoogle Scholar
  28. 28.
    Yao K, et al. Novel magnified endoscopic findings of microvascular architecture in intramucosal gastric cancer. Gastrointest Endosc. 2002;56:279–84.CrossRefGoogle Scholar
  29. 29.
    Yoshida T, et al. Narrow-band imaging system with magnifying endoscopy for superficial esophageal lesions. Gastrointest Endosc. 2004;59:288–95.CrossRefGoogle Scholar
  30. 30.
    Gono K, et al. Appearance of enhanced tissue features in narrow-band endoscopic imaging. J Biomed Opt. 2004;9:568–77.CrossRefGoogle Scholar
  31. 31.
    Toyoda H, et al. Detection of intestinal metaplasia in distal esophagus and esophagogastric junction by enhanced-magnification endoscopy. Gastrointest Endosc. 2004;59:15–21.CrossRefGoogle Scholar
  32. 32.
    Tanaka S, et al. Aim to unify the narrow band imaging (NBI) magnifying classification for colorectal tumors: current status in Japan from a summary of the consensus symposium in the 79th Annual Meeting of the Japan Gastroenterological Endoscopy Society. Dig Endosc. 2011;23(Suppl 1):131–9.CrossRefGoogle Scholar
  33. 33.
    Hayashi N, et al. Endoscopic prediction of deep submucosal invasive carcinoma: validation of the narrow-band imaging international colorectal endoscopic (NICE) classification. Gastrointest Endosc. 2013;78:625–32.CrossRefGoogle Scholar
  34. 34.
    Okada K, et al. Diagnosis of undifferentiated type early gastric cancers by magnification endoscopy with narrow-band imaging. J Gastroenterol Hepatol. 2011;26:1262–9.CrossRefGoogle Scholar
  35. 35.
    Ezoe Y, et al. Magnifying narrowband imaging is more accurate than conventional white-light imaging in diagnosis of gastric mucosal cancer. Gastroenterology. 2011;141:2017–25. e2013.CrossRefGoogle Scholar
  36. 36.
    Abe S, et al. Depth-predicting score for differentiated early gastric cancer. Gastric Cancer. 2011;14:35–40.CrossRefGoogle Scholar
  37. 37.
    Tanaka K, et al. Features of early gastric cancer and gastric adenoma by enhanced-magnification endoscopy. J Gastroenterol. 2006;41:332–8.CrossRefGoogle Scholar
  38. 38.
    Gatenby PA, et al. Relevance of the detection of intestinal metaplasia in non-dysplastic columnar-lined oesophagus. Scand J Gastroenterol. 2008;43:524–30.CrossRefGoogle Scholar
  39. 39.
    Kelty CJ, et al. Barrett’s oesophagus: intestinal metaplasia is not essential for cancer risk. Scand J Gastroenterol. 2007;42:1271–4.CrossRefGoogle Scholar
  40. 40.
    Riddell RH, et al. Definition of Barrett’s esophagus: time for a rethink--is intestinal metaplasia dead? Am J Gastroenterol. 2009;104:2588–94.CrossRefGoogle Scholar
  41. 41.
    Anagnostopoulos GK, et al. Novel endoscopic observation in Barrett’s oesophagus using high resolution magnification endoscopy and narrow band imaging. Aliment Pharmacol Ther. 2007;26:501–7.CrossRefGoogle Scholar
  42. 42.
    Goda K, et al. Usefulness of magnifying endoscopy with narrow band imaging for the detection of specialized intestinal metaplasia in columnar-lined esophagus and Barrett’s adenocarcinoma. Gastrointest Endosc. 2007;65:36–46.CrossRefGoogle Scholar
  43. 43.
    Kara MA, et al. Detection and classification of the mucosal and vascular patterns (mucosal morphology) in Barrett’s esophagus by using narrow band imaging. Gastrointest Endosc. 2006;64:155–66.CrossRefGoogle Scholar
  44. 44.
    Sharma P, et al. The utility of a novel narrow band imaging endoscopy system in patients with Barrett’s esophagus. Gastrointest Endosc. 2006;64:167–75.CrossRefGoogle Scholar
  45. 45.
    Sharma P, et al. Development and validation of a classification system to identify high-grade dysplasia and esophageal adenocarcinoma in Barrett’s esophagus using narrow-band imaging. Gastroenterology. 2016;150:591–8.CrossRefGoogle Scholar
  46. 46.
    Pech O, et al. Prospective evaluation of the macroscopic types and location of early Barrett’s neoplasia in 380 lesions. Endoscopy. 2007;39:588–93.CrossRefGoogle Scholar

Copyright information

© Springer International Publishing 2019

Authors and Affiliations

  1. 1.Department of Internal Medicine I, Paracelsus Medical UniversitySalzburgAustria
  2. 2.Department of Digestive DiseasesHôpital Eduard HerriotLyonFrance
  3. 3.Department of Gastroenterology and HepatologyGunma University HospitalMaebashiJapan

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