Antipsychotic Medication-Induced Weight Gain

  • Leon I. Igel


A 35-year-old man is referred to you by his psychiatrist for assistance with weight management. The patient has a history of class 2 obesity (height 70 in, weight 258 lb, BMI 37 kg/m2) and bipolar disorder managed with olanzapine. The olanzapine was started 1 year ago after SSRIs and SNRIs proved ineffective. While olanzapine has been helpful with respect to mood, the patient has gained 19 lb since initiating therapy. The patient’s psychiatrist is hopeful that, together, you can formulate a plan to address the patient’s weight while maintaining mood stability.


Antipsychotic medication Weight gain Bipolar disorder Olanzapine Obesity 


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© Springer Nature Switzerland AG 2019

Authors and Affiliations

  1. 1.Comprehensive Weight Control Center, Division of Endocrinology, Diabetes and MetabolismWeill Cornell Medical CollegeNew YorkUSA

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