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Vesicoureteral Reflux (VUR): Endoscopic Treatment

  • Hiroshi Murakami
  • Geoffrey J. Lane
  • Atsuyuki YamatakaEmail author
Chapter

Abstract

Vesicoureteral reflux (VUR) is one of the most common urologic morbidities in children, with an estimated prevalence of approximately 1% of the general pediatric population, but which can be as high as 30% in children with a history of febrile urinary tract infection (UTI) [1, 2]. The goals of treating a child with VUR are (1) to prevent recurring febrile UTI, (2) to prevent renal damage, and (3) to minimize/prevent adverse effects of treatment [3].

References

  1. 1.
    Kirsch A, Arlen A, Lackgren G. Current trends in dextranomer hyaluronic acid copolymer (Deflux) injection technique for endoscopic treatment of vesicoureteral reflux. Urology. 2014;84(2):462–8.CrossRefGoogle Scholar
  2. 2.
    Skoog SJ, Peters CA, Arant BS Jr, Copp HL, Elder JS, Hudson RG, et al. Pediatric vesicoureteral reflux guidelines panel summary report: clinical practice guidelines for screening siblings of children with vesicoureteral reflux and neonates/infants with prenatal hydronephrosis. J Urol. 2010;184(3):1145–51.CrossRefGoogle Scholar
  3. 3.
    Peters CA, Skoog SJ, Arant BS Jr, Copp HL, Elder JS, Hudson RG, et al. Summary of the AUA guideline on management of primary vesicoureteral reflux in children. J Urol. 2010;184(3):1134–44.CrossRefGoogle Scholar
  4. 4.
    O’Donnell B, Puri P. Treatment of vesicoureteric reflux by endoscopic injection of Teflon. J Urol. 2002;167:1808–9.CrossRefGoogle Scholar
  5. 5.
    Kirsch AJ, Perez-Brayfield M, Smith EA, Scherz HC. The modified Sting procedure to correct vesicoureteral reflux: improved results with submucosal implantation within the intramural ureter. J Urol. 2004;171(6):2413–6.CrossRefGoogle Scholar
  6. 6.
    Cerwinka W, Scherz H, Kirsch AJ. Dynamic hydrodistention classification of the ureter and the double HIT method to correct vesicoureteral reflux. Arch Esp Urol. 2008;61:882–7.CrossRefGoogle Scholar
  7. 7.
    Puri P, Pirker M, Mohanan N, Dawrant M, Dass L, Colhoun E. Subureteral dextranomer/hyaluronic acid injection as first line treatment in the management of high grade vesicoureteral reflux. J Urol. 2006;176:1856–9.CrossRefGoogle Scholar
  8. 8.
    Ormaechea M, Ruiz E, Denes E, Gimenez F, Denes FT, Moldes J, et al. New tissue bulking agent (polyacrylate polyalcohol) for treating vesicoureteral reflux: preliminary results in children. J Urol. 2010;183(2):714–7.CrossRefGoogle Scholar
  9. 9.
    Warchol S, Krzemien G, Szmigielska A, Bombinski P, Toth K, Dudek-Warchol T. Endoscopic correction of vesicoureteral reflux in children using polyacrylate-polyalcohol copolymer (Vantris): 5-years of prospective follow-up. Cent European J Urol. 2017;70(3):314–9.PubMedPubMedCentralGoogle Scholar
  10. 10.
    Romain J, Fourcade L, Centi J, Blanc P, Masselin MC, Lescure V, et al. Delayed-onset ureteral obstruction and calcification masquerading as renal colic following Deflux injection. Urology. 2016;94:218–20.CrossRefGoogle Scholar
  11. 11.
    Chung JM, Park CS, Lee SD. Postoperative ureteral obstruction after endoscopic treatment for vesicoureteral reflux. Korean J Urol. 2015;56(7):533–9.CrossRefGoogle Scholar
  12. 12.
    Ben-Meir D, Bahouth Z, Halachmi S. Late-onset uretero-vesical junction obstruction following endoscopic injection of bulking material for the treatment of vesico-ureteral reflux. Urology. 2017;101:60–2.CrossRefGoogle Scholar

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Hiroshi Murakami
    • 1
  • Geoffrey J. Lane
    • 1
  • Atsuyuki Yamataka
    • 1
    Email author
  1. 1.Department of Pediatric General and Urogenital SurgeryJuntendo University School of MedicineTokyoJapan

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