Haemodialysis-Associated Amyloidosis

  • Reiner Bartl
  • Christoph Bartl


One form of amyloidosis, β2-microglobulin, is characteristic in renal dialysis patients. Amyloid is deposited in the skeleton and periosteal tissues and is a further manifestation of renal bone disease. About 200 mg of this protein are produced each day on cell surfaces, normally filtered by the glomeruli and catabolised in the tubuli. However, this low-molecular-weight protein does not filter well through dialysis membranes and as a consequence accumulates in tissues. After 10 or more years of dialysis, about 70% of patients are affected.


Subchondral bone Carpal tunnel syndrome Carpal tunnel Soft tissue masses Bone cyst 

Copyright information

© Springer Nature Switzerland AG 2019

Authors and Affiliations

  • Reiner Bartl
    • 1
  • Christoph Bartl
    • 1
    • 2
  1. 1.Osteoporosis and Bone CenterMunichGermany
  2. 2.Center of Orthopaedics and Sports MedicineMunichGermany

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