The Patient with “Hypocalcaemia”
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Hypocalcaemia is defined as a plasma or serum concentration of total calcium <2.20 mmol/L (<8.8 mg/dL) with normal plasma or serum protein concentration or a plasma or serum concentration of ionised calcium <1.17 mmol/L (4.7 mg/dL). In healthy people only 48% of calcium, in the ionised form, is metabolically active. The acid-base balance is also important, because an acidosis is associated with a higher level of ionised calcium, while an alkalosis with lower level of ionised calcium shows a higher probability of hypocalcaemia symptoms.