Épidémiologie de la fertilité masculine Évolution de la qualité du sperme au cours des dernières décennies
Résumé
Au cours des dernières décennies, une détérioration de la fonction de reproduction mâle a été rapportée dans de nombreuses espèces (1). La plupart des observations ont été faites dans la faune sauvage. Dans de nombreux cas, il existe un lien avec une pollution de l’environnement. Parmi les milliers de composés chimiques issus des activités humaines, ont particulièrement été mis en cause des composés industriels (phtala-tes, biphényls polychlorés (PCB), bisphénol A, etc.) et de l’agriculture (par exemple, le 1,1,1-trichloro-2,2-bis (4-chlorophenyl) éthane, DDT, de nombreux herbicides et fongicides) qualifiés de xénohormones ou de perturbateurs endocriniens (PE). Des anomalies variées du développement de l’appareil reproducteur et de la fonction de reproduction mâle ont été observées suite à une exposition aux PE chez divers animaux comme les alligators d’un lac de Floride contaminé par du DDT (2) et, dans la même région, les panthères mâles (3), les poissons de plusieurs rivières anglaises (4) ...
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