Traité de nutrition artificielle de l’adulte pp 455-472 | Cite as
Nutrition, immunité et inflammation
Abstrait
Depuis le début des années 1970, ľexistence ďune relation étroite entre le statut nutritionnel et les capacités de réponse inflammatoire et immunitaire (RII) à ľagression est admise. Les premiers travaux ont montré qu’une dénutrition protéino-énergétique, altérait significativement la réponse immunitaire, tant innée qu’acquise, augmentant ainsi le risque infectieux et le taux de mortalité des malades les plus dénutris. Plus récemment, il est également apparu que ľobésité interférait avec la RII. Ces relations et les principaux mécanismes qui y conduisent seront brièvement revus dans la première partie de ce chapitre, après un rappel des étapes clés de la RII.
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