Transition from the Fetal to the Neonatal Circulation

Chapter

Abstract

To understand the rules and limitations of neonatal circulation in normal hearts and in those with congenital diseases, one must remember and understand the basic rules of heart physiology and apply them to the fetal and the neonatal circulations, with emphasis on the cardiovascular adaptation to the changes occurring at birth.

References and Recommended Reading

  1. 1.
    Sidi D, Teitel DF, Kuipers JR, Heymann MA, Rudolph AM. Effect of beta-adrenergic receptor blockade on responses to acute hypoxemia in lambs. Pediatr Res. 1988;23:229–234.PubMedCrossRefGoogle Scholar
  2. 2.
    Bernstein D, Teitel D, Sidi D, Heymann MA, Rudolph AM. Redistribution of regional blood flow and oxygen delivery in experimental cyanotic heart disease in newborn lambs. Pediatr Res. 1987;22:389–393.PubMedCrossRefGoogle Scholar
  3. 3.
    Teitel DF, Sidi D, Chin T, Brett C, Heymann MA, Rudolph AM. Developmental changes in myocardial contractile reserve in the lamb. Pediatr Res. 1985;19:948–955.PubMedCrossRefGoogle Scholar
  4. 4.
    Sidi D, Kuipers JR, Teitel D, Heymann MA, Rudolph AM. Developmental changes in oxygenation and circulatory responses to hypoxemia in lambs. Am J Physiol. 1983;245:H674–H682.PubMedGoogle Scholar
  5. 5.
    Kuipers JR, Sidi D, Heymann MA, Rudolph AM. Comparison of methods of measuring cardiac output in newborn lambs. Pediatr Res. 1982;16:594–598.PubMedCrossRefGoogle Scholar
  6. 6.
    Takahashi Y, de Vroomen M, Gournay V, Roman C, Rudolph AM, Heymann MA. Mechanisms of adrenomedullin-induced increase of pulmonary blood flow in fetal sheep. Pediatr Res. 1999;45:276–281.PubMedCrossRefGoogle Scholar
  7. 7.
    Schmidt KG, Silverman NH, Rudolph AM. Phasic flow events at the aortic isthmus-ductus arteriosus junction and branch pulmonary artery evaluated by multimodal ultrasonography in fetal lambs. Am J Obstet Gynecol. 1998;179:1338–1347.PubMedCrossRefGoogle Scholar
  8. 8.
    Iwamoto HS, Teitel DF, Rudolph AM. Effects of lung distension and spontaneous fetal breathing on hemodynamics in sheep. Pediatr Res. 1993;33:639–644.PubMedCrossRefGoogle Scholar
  9. 9.
    Iwamoto HS, Teitel DF, Rudolph AM. Effect of birth-related events on metabolism in fetal sheep. Pediatr Res. 1991;30:158–164.PubMedCrossRefGoogle Scholar
  10. 10.
    Jensen A, Roman C, Rudolph AM. Effects of reducing uterine blood flow on fetal blood flow distribution and oxygen delivery. J Dev Physiol. 1991;15:309–323.PubMedGoogle Scholar
  11. 11.
    Teitel DF, Iwamoto HS, Rudolph AM. Changes in the pulmonary circulation during birth-related events. Pediatr Res. 1990;27:372.PubMedCrossRefGoogle Scholar
  12. 12.
    Hawkins J, Van Hare GF, Schmidt KG, Rudolph AM. Effects of increasing afterload on left ventricular output in fetal lambs. Circ Res. 1989;65:127–134.PubMedCrossRefGoogle Scholar
  13. 13.
    Rudolph AM, Iwamoto HS, Teitel DF. Circulatory changes at birth. J Perinat Med. 1988;16:9–21.PubMedCrossRefGoogle Scholar
  14. 14.
    Iwamoto HS, Teitel D, Rudolph AM. Effects of birth-related events on blood flow distribution. Pediatr Res. 1987;22:634–640.PubMedCrossRefGoogle Scholar
  15. 15.
    Teitel DF, Iwamoto HS, Rudolph AM. Effects of birth-related events on central blood flow patterns. Pediatr Res. 1987;22:557–566.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag London Limited 2009

Authors and Affiliations

  1. 1.Service of Pediatric Cardiology, Department of PediatricsHôpital Necker-Enfants Malades, University of Paris VParisFrance

Personalised recommendations