Meningiomas pp 31-43 | Cite as

Pathology of Meningiomas

  • Richard A. Prayson

The vast majority of meningiomas arise in the meninges from arachnoidal cap cells that are normally present in small nests. Harvey Cushing first introduced the term meningioma in 1922 to designate a group of tumors, which arose from the meninges of the brain and spinal cord [1]. Previous to Cushing, these tumors had been referred to by a variety of designations, including angioendothelioma, arachnoidal fibroblastoma, dural endothelioma, dural sarcoma, endotheliosis of the meninges, meningeal fibroblastoma, meningoblastoma, mesothelioma of the meninges, sarcoma of the dura, and fungus of the dura mater. In 1922, Oberling was one of the first to divide meningiomas into subtypes [2]. This classification was based on the concept of cell structure of the meninges and included three different groups. A few years later, Roussy and Cornil developed a similar three-group classification based on the cytologic structure of these neoplasms [3]. In 1930, del Rio Hortega devised a classification for meningiomas, which was based on structural and architectural features of the tumor [4]. In the following year, the classification began to expand with the recognition of the phenotypic variability of these tumors.


Intracranial Meningioma Psammoma Body Atypical Meningioma Malignant Meningioma Clear Cell Meningioma 
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© Springer-Verlag London Limited 2009

Authors and Affiliations

  • Richard A. Prayson
    • 1
  1. 1.Department of NeuropathologyCleveland ClinicClevelandUSA

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