Ghrelin Responses to Acute Exercise and Training

  • Jaak JürimäeEmail author
  • Toivo Jürimäe
Part of the Contemporary Endocrinology book series (COE)


Energy homeostasis is regulated by a complex neuroendocrine system including central and peripheral tissues (1, 2). Therefore, the hypothalamus in the brain appears to centrally integrate the various metabolic and hormonal signals, and has an important role in the central responses to changes in energy balance (3). Important in this regulatory system is also the existence of several gut, pancreatic and adipose tissue hormones that communicate the status of body energy stores to the hypothalamus (1). Among the gut hormones secreted in response to nutrient ingestion, ghrelin, peptide YY, cholecystokinin and glucagon-like peptide-1 are involved in regulating both acute and chronic energy homeostasis (4, 5). Therefore, peptide YY, cholecystokinin and glucagon-like peptide-1 function as negative feedback signals, suppressing appetite and food intake once nutrients are ingested (5, 6), and peptide YY has received more attention among appetite and food consumption suppressing peptides (4, 6, 7, 8, 9). In contrast, to date, ghrelin remains unique as the only known circulating hormone that stimulates appetite and food consumption (6, 10). This chapter focuses on the available ­information about the effects of acute exercise and chronic training on the secretion of ghrelin.


Ghrelin Level Acute Exercise Negative Energy Balance Ghrelin Concentration Total Ghrelin 
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© Springer Science+Business Media New York 2013

Authors and Affiliations

  1. 1.Institute of Sport Pedagogy and Coaching SciencesUniversity of TartuTartuEstonia

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