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Endoscopic Features of Eosinophilic Esophagitis

  • David A. Leiman
  • Gary W. FalkEmail author
Chapter
Part of the Clinical Gastroenterology book series (CG)

Abstract

Eosinophilic esophagitis (EoE) is a chronic inflammatory disorder of children and adults. The disease is defined by clinicopathologic criteria, including symptoms of dysphagia and food impaction, esophageal biopsies with ≥15 eosinophils per high powered field and lack of response to antisecretory therapy. Patients with eosinophilic esophagitis have a wide variety of endoscopic findings and the disease does not have a uniform endoscopic appearance. In fact, one study suggested that only 38% of individuals thought to have eosinophilic esophagitis at the time of endoscopy had histologic confirmation of the disease and a subset of patients may also have an entirely normal appearing esophagus! Furthermore, endoscopic findings may vary by age. Endoscopy plays a key role in the diagnosis of EoE patients and the varied endoscopic features of this disease are the focus of this chapter.

Keywords

Eosinophilic esophagitis Dysphagia Food impaction Biopsy Endoscopy 

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  1. 1.Department of MedicineHospital of the University of Pennsylvania, Perelman School of MedicinePhiladelphiaUSA
  2. 2.Department of Medicine, Division of GastroenterologyHospital of the University of PennsylvaniaPhiladelphiaUSA

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