In Vitro and In Vivo Immunomodulatory and Anti-allergic Effects of Agaricus blazei Murill

Chapter
First Online:
Part of the Nutrition and Health book series (NH)

Key Points

Agaricus blazei Murill extract appears to have an effect on the changing pattern of splenic lymphocyte subsets, particularly cytotoxic or natural killer cells. A. blazei Murill extract contains potent Th1 cytokine producing constituents. Oral administration of A. blazei Murill extract down-regulates serum IgE levels by enhancing Th1 response.

Key Words

Agaricus blazei Murill anti-allergy immunomodulatory activity interferon-γ (IFN-γ) interleukin (IL) Th1/Th2 balance β-glucan 
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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Professor Laboratory of Glyco-chain Biochemistry, Graduate School of Agricultural ScienceKobe UniversityKobeJapan

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