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Vascular Parkinsonism

  • Roongroj Bhidayasiri
  • Daniel Tarsy
Chapter
Part of the Current Clinical Neurology book series (CCNEU)

Abstract

Vascular parkinsonism (VP), originally known as arteriosclerotic parkinsonism, is a heterogeneous but clinically recognizable entity which is comprised of predominantly “lower body parkinsonism,” postural instability, and falls. In comparison with Parkinson’s disease (PD), patients with VP tend to be older, have a shorter duration of illness, may have a stepwise decline, present with symmetrical gait difficulties, are less responsive to levodopa, and are more prone to postural instability, falls, and dementia. Pyramidal signs, pseudobulbar palsy, and incontinence are commonly present. While no specific abnormal structural imaging pattern is suggestive of VP, brain CT and MRI often demonstrate evidence of vascular impairment with frequent involvement of more than one vascular territory and abnormalities in periventricular and subcortical white matter and basal ganglia.

Keywords

Basal Ganglion Stride Length Postural Instability Subcortical White Matter Pyramidal Sign 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Supplementary material

Vascular parkinsonism.mp4 (MP4 57,432KB)

Motor examination reveals relatively mild parkinsonism in upper extremities. Voice is hypophonic and monotonic. Signs of parkinsonism predominantly affect the lower extremities with short stride length, shuffling gait, and occasional freezing of gait. Freezing of gait could be overcome by stepping over obstacles. Pull testing is positive.

References

  1. 1.
    Winnikates J, Jankovic J. Clinical correlates of vascular parkinsonism. Arch Neurol. 1999; 56:98–102.CrossRefGoogle Scholar
  2. 2.
    Zijlmans JCM, Daniel SE, Hughes AJ, et al. Clinicopathological investigation of vascular parkinsonism, including clinical criteria for diagnosis. Mov Disord. 2004;19:630–40.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Roongroj Bhidayasiri
    • 1
    • 2
  • Daniel Tarsy
    • 3
  1. 1.Chulalongkorn Center of Excellence on Parkinson’s Disease and Related DisordersChulalongkorn University HospitalBangkokThailand
  2. 2.Department of NeurologyDavid Geffen School of Medicine at UCLALos AngelesUSA
  3. 3.Department of NeurologyHarvard Medical School Beth Israel Deaconess Medical CenterBostonUSA

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