Coronary CT Angiography for Screening, Risk Stratification, and Management of Asymptomatic Patients: State of the Evidence

  • Felix G. MeinelEmail author
  • Matthias Renker
Part of the Contemporary Medical Imaging book series (CMI)


Established guidelines generally do not recommend using coronary CT angiography (coronary CTA) to screen for coronary artery disease (CAD) in asymptomatic individuals. Nevertheless, many institutions perform coronary CTA examinations in asymptomatic individuals as part of clinical trials or screening programs. Over the past few years, an increasing body of evidence on the potential role of coronary CTA in asymptomatic individuals has emerged from these institutions. This book chapter reviews the recent literature on coronary CTA screening for CAD in asymptomatic individuals. The chapter is organized along several leading questions: (a) How frequently is coronary CTA performed in asymptomatic individuals? (b) What is the diagnostic yield of coronary CTA in asymptomatic individuals? Can we identify specific high-risk groups with high diagnostic yield? (c) What is the prognostic value of coronary CTA screening in asymptomatic patients? Does it improve risk stratification beyond traditional risk factors? (d) What would be the consequences for management, if CAD was detected in asymptomatic individuals? (e) Do we have evidence that coronary CTA screening for CAD improves patients’ outcome?


Coronary CT angiography Cardiac CT Asymptomatic patients with low cardiac risk Screening in cardiac CT Risk stratification with cardiac CT Low cardiac risk patients 


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Copyright information

© Humana Press 2019

Authors and Affiliations

  1. 1.Department of Diagnostic and Interventional Radiology, Rostock University Medical CenterRostockGermany
  2. 2.Department of CardiologyKerckhoff Heart and Thorax CenterBad NauheimGermany

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