Clinical Application of the Coronary Artery Calcium Score and Implications for Cardiovascular Disease Prevention

  • Pamela B. MorrisEmail author
  • Michael D. Shapiro
Part of the Contemporary Medical Imaging book series (CMI)


Cardiovascular disease continues to be the leading cause of morbidity and mortality around the globe, and CACS is an important tool to readily identify individuals at high risk of events to initiate early lifesaving preventive interventions. The assessment of subclinical coronary atherosclerosis by CACS has been shown to be a robust predictor of both near- and long-term clinical ASCVD events and provides information that outperforms traditional risk factor-based assessments. Current guidelines focus on the consideration of CACS in intermediate-risk patients to inform clinical decision making for initiation of preventive therapies. Knowledge of the subclinical disease can improve adherence to preventive medications and lifestyle interventions.


Coronary artery calcium score Cardiovascular disease prevention Atherosclerotic cardiovascular disease risk Cardiovascular risk assessment Prediction of coronary heart disease 


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Copyright information

© Humana Press 2019

Authors and Affiliations

  1. 1.Seinsheimer Cardiovascular Health Program, Department of Medicine and CardiologyMedical University of South CarolinaCharlestonUSA
  2. 2.Department of Medicine, Division of Cardiovascular MedicineOregon Health & Science UniversityPortlandUSA

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