Asymptomatic Atherosclerosis pp 707-722 | Cite as
Last Chance for Prevention (Acute Prevention): Identification of Prodromal Symptoms and Early Heart Attack Care
Abstract
Atherosclerotic cardiovascular disease is the leading cause of mortality and morbidity in the USA. Millions of dollars are spent each year for research efforts to find the best therapy for reperfusion of acutely closed coronary arteries, which would otherwise lead to acute myocardial infarction (MI). As with other disease states, heart attacks have beginnings. Chest discomfort before severe chest pain represents a clinical ischemia marker, and indicates live myocardium in jeopardy that often precedes cardiac arrest or acute MI. The intermittent or stuttering symptoms that precede MI are referred to as “prodromal symptoms.” These symptoms correlate with cyclic ST changes and repeated episodes of spontaneous reperfusion and occlusion, occurring during a period of hours or days before the ischemia proceeds to damage. Premonitory, or preinfarct angina, has been associated with improved outcomes in patients with acute MI by providing ischemic preconditioning or opening collateral vessels. Acute MI prevention through prodromal symptoms recognition represents an opportunity for reducing heart attack fatality. In conjunction with the Screening for Heart Attack Prevention and Eradication (SHAPE) initiative, the Early Heart Attack Care program emphasizes prodromal symptom recognition in at-risk populations, facilitating early detection and prevention of fatal heart attacks. Similarly, the strategy behind the chest pain centre movement in the USA is to prepare the hospitals for proper screening of patients suspected of acute coronary syndromes and to detect patients with prodromal symptoms in the community. In the era of the remarkably facilitated communication of Google, iPhone, Facebook, and Twitter, new developments are urgently needed to incorporate information technology into the early detection of prodromal symptoms. An example of such a development is proposed under “http://www.checkmyheart.com” in this chapter.
Key words
Prodromal symptoms Preinfarct angina Chest pain centers Early heart attack careAbbreviations
- ACS
Acute coronary syndrome
- CCU
Coronary care unit
- CDU
Clinical decision unit
- CHD
Coronary heart disease
- CHEPER
Chest pain evaluation registry
- CMS
Centers for medicare and medicaid services
- CPC
Chest pain centers
- CRUSADE
Can rapid risk stratification of unstable angina patients suppress adverse outcomes with early implementation of the American College of Cardiology/American Heart Association Guidelines – National Quality Improvement Initiative registry
- ECG
Electrocardiogram
- ED
Emergency department
- EHAC
Early heart attack care
- ER
Emergency room
- GUSTO
Global utilization of strategies to open occluded coronary vessels
- HCFA
Health care financing administration
- MI
Myocardial infarction
- MITI
Myocardial infarction triage and intervention
- NEJM
New England journal of medicine
- NHAEP
National heart attack alert program
- NSTEMI
Non ST elevation myocardial infarction
- OU
Observation unit
- pPCI
Primary percutaneous coronary intervention
- SCPC
Society of chest pain centers
- SHAPE
Screening for heart attack prevention and education
- SHAPE
Society for heart attack prevention and eradication
- STEMI
ST elevation myocardial infarction
- TIMI
Thrombolysis in acute myocardial infarction
- tPA
Tissue plasminogen activator
- USPHS
United States public health service
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