9.1 Introduction

Malaria is the most significant parasitic disease of human beings and remains a major cause of morbidity, anemia, and mortality worldwide. Malaria currently accounts for approximately 200 million morbid episodes and 2–3 million deaths each year, estimates that have been increasing over the last three decades [1]. The disease is caused by protozoan organisms of the genus Plasmodium, which invade and replicate within red blood cells (RBCs), a process resulting in the manifestations of disease, including cyclical fevers, anemia, convulsions, and death. The parasite is transmitted from person to person by biting anopheline mosquitoes. There are four malaria species that infect humans: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, and Plasmodium ovale. They are distributed in varying degrees throughout the tropical world and in some more temperate areas, wherever ecological and sociological conditions favor sufficient interactions between humans,...


Preschool Child Severe Malaria Cerebral Malaria Parasite Density Iron Supplementation 
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Copyright information

© Humana Press, a part of Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Anuraj H. Shankar
    • 1
  1. 1.World Health OrganizationJakartaIndonesia

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