Steroidogenic Enzymes in Leydig Cells

  • Anita H. Payne
Chapter
Part of the Contemporary Endocrinology book series (COE)

Abstract

This chapter describes the enzymes expressed in Leydig cells that are required for the biosynthesis of testosterone from cholesterol, as well as the two enzymes, steroid 5 areductase and P450arom, that metabolize testosterone to dihydrotestosterone and estradiol, respectively. The emphasis is on human and mouse enzymes.

Key Words

CYP11A CYP17A CYP19A 3β-HSD 17β-HSD Leydig cell P450arom P450c17 P450scc steroidogenesis steroid-α-reductase 
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Copyright information

© Humana Press Inc., Totowa, NJ 2007

Authors and Affiliations

  • Anita H. Payne
    • 1
  1. 1.Division of Reproductive Biology, Department of Obstetrics and GynecologyStanford University School of MedicineStanford

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