Appropriate Antibiotic Use for Treatment of Nonspecific Upper Respiratory Infections, Rhinosinusitis, and Acute Bronchitis in Adults

  • Tina H. Degnan
  • Neil S. Skolnik
Part of the Current Clinical Practice book series (CCP)


Acute sinusitis, bronchitis, pharyngitis, and nonspecific upper respiratory tract infections (URIs) account for the majority of antibiotics prescribed by primary care physicians in the United States. The emergence of antibiotic-resistant bacteria in the community setting is now an issue for individual patients as well as society at large, and it is the responsibility of all clinicians to limit antibiotic treatment to those patients who are most likely to benefit from it. The vast majority of acute respiratory infections are caused by viruses. Antibiotic treatment of patients with these infections selects for resistant nasopharyngeal bacteria, acutely increasing the spread of resistant pathogens through secretions and predisposing the treated patient to more serious bacterial infections in the future. The guidelines summarized in this chapter were designed by a panel of physicians representing family medicine, internal medicine, emergency medicine, and infectious diseases to provide a practical approach to the appropriate diagnosis and treatment of previously healthy adults with nonspecific URI, acute sinusitis, or acute bronchitis in the ambulatory care setting. Recommendations for the diagnosis and treatment of pharyngitis are provided in a separate chapter.


Respiratory Syncytial Virus Antibiotic Treatment Acute Bronchitis Bordetella Pertussis Acute Sinusitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


  1. 1.
    Principles of Appropriate Antibiotic Use for Treatment of Acute Respiratory Tract Infections in Adults: background, Specific Aims, and Methods (2001) Ann Inter Med 134:479–486.Google Scholar
  2. 2.
    Principles of Appropriate Antibiotic Use for Treatment of Nonspecific Respiratory Tract Infections in Adults (2001) Ann Intern Med 134:487–489.Google Scholar
  3. 3.
    Principles of Appropriate Antibiotic Use for Acute Sinusitis in Adults (2001) Ann Intern Med 134:495–497.Google Scholar
  4. 4.
    Principles of Appropriate Antibiotic Use for Treatment of Acute Bronchitis in Adults (2001) Ann Intern Med 134:518–520.Google Scholar
  5. 5.
    Slavin RG. The diagnosis and management of sinusitis: a practice parameter update. J Allergy Clin Immunol 2005;116:S13–47.PubMedCrossRefGoogle Scholar

Copyright information

© Humana Press Inc., Totowa, NJ 2007

Authors and Affiliations

  • Tina H. Degnan
    • 1
  • Neil S. Skolnik
    • 2
    • 3
  1. 1.Family Medicine ResidencyAbington Memorial HospitalAbington
  2. 2.Family Medicine Residency ProgramAbington Memorial HospitalAbington
  3. 3.Temple University School of MedicinePhiladelphia

Personalised recommendations