Squamous Cell Head and Neck Cancer pp 1-26 | Cite as
Head and Neck Squamous Cell Cancers in the Nonsmoker-Nondrinker
Chapter
Abstract
The vast majority of patients with head and neck squamous cell carcinoma (HNSCC) report a history of tobacco and alcohol use. The risk of oral cancer increases as a function of both intensity and duration of each exposure, indicating that alcohol and tobacco act synergistically to promote cancer development (1, 2, 3).
Keywords
Oral Cavity Oral Cancer Natl Cancer Inst Laryngeal Cancer Environmental Tobacco Smoke Exposure
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References
- 1.Franceschi S, Levi F, La Vecchia C, et al. Comparison of the effect of smoking and alcohol drinking between oral and pharyngeal cancer. Int J Cancer 1999; 83:1–4.PubMedCrossRefGoogle Scholar
- 2.Lewin F, Norell SE, Johansson H, et al. Smoking tobacco, oral snuff, and alcohol in the etiology of squamous cell carcinoma of the head and neck: a population-based case-referent study in Sweden. Cancer 1998; 82:1367–1375.PubMedCrossRefGoogle Scholar
- 3.Day GL, Blot WJ, Austin DF, et al. Racial differences in risk of oral and pharyngeal cancer: alcohol, tobacco, and other determinants. J Natl Cancer Inst 1993; 85:465–473.PubMedCrossRefGoogle Scholar
- 4.Jaber MA, Porter SR, Scully C, Gilthorpe MS, Bedi R. The role of alcohol in non-smokers and tobacco in non-drinkers in the aetiology of oral epithelial dysplasia. Int J Cancer 1998; 77:333–336.PubMedCrossRefGoogle Scholar
- 5.Talamini R, La Vecchia C, Levi F, Conti E, Favero A, Franceschi S. Cancer of the oral cavity and pharynx in nonsmokers who drink alcohol and in nondrinkers who smoke tobacco. J Natl Cancer Inst 1998; 90:1901–1903.PubMedCrossRefGoogle Scholar
- 6.Castellsague X, Quintana MJ, Martinez MC, et al. The role of type of tobacco and type of alcoholic beverage in oral carcinogenesis. Int J Cancer 2004; 108:741–749.PubMedCrossRefGoogle Scholar
- 7.Inagaki S, Esaka Y, Deyashiki Y, Sako M, Goto M. Analysis of DNA adducts of acetaldehyde by liquid chromatography-mass spectrometry. J Chromatogr A 2003; 987:341–347.PubMedCrossRefGoogle Scholar
- 8.Edenberg HJ, Brown CJ. Regulation of human alcohol dehydrogenase genes. Pharmacogenetics 1992; 2:185–196.PubMedCrossRefGoogle Scholar
- 9.Harty LC, Caporaso NE, Hayes RB, et al. Alcohol dehydrogenase 3 genotype and risk of oral cavity and pharyngeal cancers. J Natl Cancer Inst 1997; 89:1698–1705.PubMedCrossRefGoogle Scholar
- 10.Bouchardy C, Hirvonen A, Coutelle C, Ward PJ, Dayer P, Benhamou S. Role of alcohol dehydrogenase 3 and cytochrome P-4502E1 genotypes in susceptibility to cancers of the upper aerodigestive tract. Int J Cancer 2000; 87:734–740.PubMedCrossRefGoogle Scholar
- 11.Coutelle C, Ward PJ, Fleury B, et al. Laryngeal and oropharyngeal cancer, and alcohol dehydrogenase 3 and glutathione S-transferase M1 polymorphisms. Hum Genet 1997; 99:319–325.PubMedCrossRefGoogle Scholar
- 12.Mashberg A, Boffetta P, Winkelman R, Garfinkel L. Tobacco smoking, alcohol drinking, and cancer of the oral cavity and oropharynx among U.S. veterans. Cancer 1993; 72:1369–1375.PubMedCrossRefGoogle Scholar
- 13.Balaram P, Sridhar H, Rajkumar T, et al. Oral cancer in southern India: the influence of smoking, drinking, paan-chewing and oral hygiene. Int J Cancer 2002; 98:440–445.PubMedCrossRefGoogle Scholar
- 14.Garrote LF, Herrero R, Reyes RM, et al. Risk factors for cancer of the oral cavity and oro-pharynx in Cuba. Br J Cancer 2001; 85:46–54.PubMedCrossRefGoogle Scholar
- 15.Salaspuro V, Salaspuro M. Synergistic effect of alcohol drinking and smoking on in vivo acetaldehyde concentration in saliva. Int J Cancer 2004; 111:480–483.PubMedCrossRefGoogle Scholar
- 16.Brugere J, Guenel P, Leclerc A, Rodriguez J. Differential effects of tobacco and alcohol in cancer of the larynx, pharynx, and mouth. Cancer 1986; 57:391–395.PubMedCrossRefGoogle Scholar
- 17.Boffetta P, Mashberg A, Winkelmann R, Garfinkel L. Carcinogenic effect of tobacco smoking and alcohol drinking on anatomic sites of the oral cavity and oropharynx. Int J Cancer 1992; 52:530–533.PubMedCrossRefGoogle Scholar
- 18.Franceschi S, Talamini R, Barra S, et al. Smoking and drinking in relation to cancers of the oral cavity, pharynx, larynx, and esophagus in northern Italy. Cancer Res 1990; 50:6502–6507.PubMedGoogle Scholar
- 19.De Stefani E, Boffetta P, Oreggia F, Mendilaharsu M, Deneo-Pellegrini H. Smoking patterns and cancer of the oral cavity and pharynx: a case-control study in Uruguay. Oral Oncol 1998; 34:340–346.PubMedCrossRefGoogle Scholar
- 20.Znaor A, Brennan P, Gajalakshmi V, et al. Independent and combined effects of tobacco smoking, chewing and alcohol drinking on the risk of oral, pharyngeal and esophageal cancers in Indian men. Int J Cancer 2003; 105:681–686.PubMedCrossRefGoogle Scholar
- 21.Zheng TZ, Boyle P, Hu HF, et al. Tobacco smoking, alcohol consumption, and risk of oral cancer: a case-control study in Beijing, People’s Republic of China. Cancer Causes Control 1990; 1:173–179.PubMedCrossRefGoogle Scholar
- 22.Talamini R, Bosetti C, La Vecchia C, et al. Combined effect of tobacco and alcohol on laryngeal cancer risk: a case-control study. Cancer Causes Control 2002; 13:957–964.PubMedCrossRefGoogle Scholar
- 23.Castelletto R, Castellsague X, Munoz N, Iscovich J, Chopita N, Jmelnitsky A. Alcohol, tobacco, diet, mate drinking, and esophageal cancer in Argentina. Cancer Epidemiol Biomarkers Prev 1994; 3:557–564.PubMedGoogle Scholar
- 24.Sankaranarayanan R, Duffy SW, Day NE, Nair MK, Padmakumary G. A case-control investigation of cancer of the oral tongue and the floor of the mouth in southern India. Int J Cancer 1989; 44:617–621.PubMedCrossRefGoogle Scholar
- 25.Hodge KM, Flynn MB, Drury T. Squamous cell carcinoma of the upper aerodigestive tract in nonusers of tobacco. Cancer 1985; 55:1232–1235.PubMedCrossRefGoogle Scholar
- 26.Sorensen DM, Lewark TM, Haney JL, Meyers AD, Krause G, Franklin WA. Absence of p53 mutations in squamous carcinomas of the tongue in nonsmoking and nondrinking patients younger than 40 years. Arch Otolaryngol Head Neck Surg 1997; 123:503–506.PubMedGoogle Scholar
- 27.Koch WM, McQuone S. Clinical and molecular aspects of squamous cell carcinoma of the head and neck in the nonsmoker and nondrinker. Curr Opin Oncol 1997; 9:257–261.PubMedGoogle Scholar
- 28.Lazarus P, Garewal HS, Sciubba J, et al. A low incidence of p53 mutations in pre-malignant lesions of the oral cavity from non-tobacco users. Int J Cancer 1995; 60:458–463.PubMedCrossRefGoogle Scholar
- 29.Schantz SP, Byers RM, Goepfert H, Shallenberger RC, Beddingfield N. The implication of tobacco use in the young adult with head and neck cancer. Cancer 1988; 62:1374–1380.PubMedCrossRefGoogle Scholar
- 30.de Boer MF, Sanderson RJ, Damhuis RA, Meeuwis CA, Knegt PP. The effects of alcohol and smoking upon the age, anatomic sites and stage in the development of cancer of the oral cavity and oropharynx in females in the south west Netherlands. Eur Arch Otorhinolaryngol 1997; 254:177–179.PubMedCrossRefGoogle Scholar
- 31.Freije JE, Beatty TW, Campbell BH, Woodson BT, Schultz CJ, Toohill RJ. Carcinoma of the larynx in patients with gastroesophageal reflux. Am J Otolaryngol 1996; 17:386–390.PubMedCrossRefGoogle Scholar
- 32.Constantinides MS, Rothstein SG, Persky MS. Squamous cell carcinoma in older patients without risk factors. Otolaryngol Head Neck Surg 1992; 106:275–277.PubMedGoogle Scholar
- 33.Agudelo D, Quer M, Leon X, Diez S, Burgues J. Laryngeal carcinoma in patients without a history of tobacco and alcohol use. Head Neck 1997; 19:200–204.PubMedCrossRefGoogle Scholar
- 34.Fouret P, Monceaux G, Temam S, Lacourreye L, St Guily JL. Human papillomavirus in head and neck squamous cell carcinomas in nonsmokers. Arch Otolaryngol Head Neck Surg 1997; 123:513–516.PubMedGoogle Scholar
- 35.Rodriguez T, Altieri A, Chatenoud L, et al. Risk factors for oral and pharyngeal cancer in young adults. Oral Oncol 2004; 40:207–213.PubMedCrossRefGoogle Scholar
- 36.Brennan JA, Boyle JO, Koch WM, et al. Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck. N Engl J Med 1995; 332:712–717.PubMedCrossRefGoogle Scholar
- 37.Muscat JE, Richie JP, Jr., Thompson S, Wynder EL. Gender differences in smoking and risk for oral cancer. Cancer Res 1996; 56:5192–5197.PubMedGoogle Scholar
- 38.Dahlstrom KR, Adler-Storthz K, Etzel CJ, et al. Human papillomavirus type 16 infection and squamous cell carcinoma of the head and neck in never-smokers: a matched pair analysis. Clin Cancer Res 2003; 9:2620–2626.PubMedGoogle Scholar
- 39.Wiseman SM, Swede H, Stoler DL, et al. Squamous cell carcinoma of the head and neck in nonsmokers and nondrinkers: an analysis of clinicopathologic characteristics and treatment outcomes. Ann Surg Oncol 2003; 10:551–557.PubMedCrossRefGoogle Scholar
- 40.Lazarus P, Stern J, Zwiebel N, Fair A, Richie JP, Jr., Schantz S. Relationship between p53 mutation incidence in oral cavity squamous cell carcinomas and patient tobacco use. Carcinogenesis 1996; 17:733–739.PubMedCrossRefGoogle Scholar
- 41.Kreimer AR, Alberg AJ, Daniel R, et al. Oral human papillomavirus infection in adults is associated with sexual behavior and HIV serostatus. J Infect Dis 2004; 189:686–698.PubMedCrossRefGoogle Scholar
- 42.Maden C, Beckmann AM, Thomas DB, et al. Human papillomaviruses, herpes simplex viruses, and the risk of oral cancer in men. Am J Epidemiol 1992; 135:1093–1102.PubMedGoogle Scholar
- 43.Schwartz SM, Daling JR, Doody DR, et al. Oral cancer risk in relation to sexual history and evidence of human papillomavirus infection. J Natl Cancer Inst 1998; 90:1626–1636.PubMedCrossRefGoogle Scholar
- 44.Doll R, Peto R, Wheatley K, Gray R, Sutherland I. Mortality in relation to smoking: 40 years’ observations on male British doctors. Bmj 1994; 309:901–911.PubMedGoogle Scholar
- 45.Gillison ML, Koch WM, Capone RB, et al. Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 2000; 92:709–720.PubMedCrossRefGoogle Scholar
- 46.Smith EM, Hoffman HT, Summersgill KS, Kirchner HL, Turek LP, Haugen TH. Human papillomavirus and risk of oral cancer. Laryngoscope 1998; 108:1098–1103.PubMedCrossRefGoogle Scholar
- 47.Koch WM, Lango M, Sewell D, Zahurak M, Sidransky D. Head and neck cancer in nonsmokers: a distinct clinical and molecular entity. Laryngoscope 1999; 109:1544–1551.PubMedCrossRefGoogle Scholar
- 48.Snijders PJ, Scholes AG, Hart CA, et al. Prevalence of mucosotropic human papillomaviruses in squamous-cell carcinoma of the head and neck. Int J Cancer 1996; 66:464–469.PubMedCrossRefGoogle Scholar
- 49.Herrero R, Castellsague X, Pawlita M, et al. Human papillomavirus and oral cancer: the International Agency for Research on Cancer multicenter study. J Natl Cancer Inst 2003; 95:1772–1783.PubMedGoogle Scholar
- 50.Smith EM, Ritchie JM, Summersgill KF, et al. Human papillomavirus in oral exfoliated cells and risk of head and neck cancer. J Natl Cancer Inst 2004; 96:449–455.PubMedGoogle Scholar
- 51.Zhang ZF, Morgenstern H, Spitz MR, et al. Environmental tobacco smoking, mutagen sensitivity, and head and neck squamous cell carcinoma. Cancer Epidemiol Biomarkers Prev 2000; 9:1043–1049.PubMedGoogle Scholar
- 52.Tan EH, Adelstein DJ, Droughton ML, Van Kirk MA, Lavertu P. Squamous cell head and neck cancer in nonsmokers. Am J Clin Oncol 1997; 20:146–150.PubMedCrossRefGoogle Scholar
- 53.Yuan JM, Wang XL, Xiang YB, Gao YT, Ross RK, Yu MC. Non-dietary risk factors for nasopharyngeal carcinoma in Shanghai, China. Int J Cancer 2000; 85:364–369.PubMedCrossRefGoogle Scholar
- 54.Rajkumar T, Sridhar H, Balaram P, et al. Oral cancer in Southern India: the influence of body size, diet, infections and sexual practices. Eur J Cancer Prev 2003; 12:135–143.PubMedCrossRefGoogle Scholar
- 55.Sanchez MJ, Martinez C, Nieto A, et al. Oral and oropharyngeal cancer in Spain: influence of dietary patterns. Eur J Cancer Prev 2003; 12:49–56.PubMedCrossRefGoogle Scholar
- 56.Fioretti F, Bosetti C, Tavani A, Franceschi S, La Vecchia C. Risk factors for oral and pharyngeal cancer in never smokers. Oral Oncol 1999; 35:375–378.PubMedCrossRefGoogle Scholar
- 57.Tavani A, Gallus S, La Vecchia C, et al. Diet and risk of oral and pharyngeal cancer. An Italian case-control study. Eur J Cancer Prev 2001; 10:191–195.PubMedCrossRefGoogle Scholar
- 58.Mackerras D, Buffler PA, Randall DE, Nichaman MZ, Pickle LW, Mason TJ. Carotene intake and the risk of laryngeal cancer in coastal Texas. Am J Epidemiol 1988; 128:980–988.PubMedGoogle Scholar
- 59.Tavani A, Negri E, Franceschi S, Barbone F, La Vecchia C. Attributable risk for laryngeal cancer in northern Italy. Cancer Epidemiol Biomarkers Prev 1994; 3:121–125.PubMedGoogle Scholar
- 60.Farrow DC, Vaughan TL, Berwick M, Lynch CF, Swanson GM, Lyon JL. Diet and nasopharyngeal cancer in a low-risk population. Int J Cancer 1998; 78:675–679.PubMedCrossRefGoogle Scholar
- 61.Hsu TC, Johnston DA, Cherry LM, et al. Sensitivity to genotoxic effects of bleomycin in humans: possible relationship to environmental carcinogenesis. Int J Cancer 1989; 43:403–409.PubMedCrossRefGoogle Scholar
- 62.Schantz SP, Zhang ZF, Spitz MS, Sun M, Hsu TC. Genetic susceptibility to head and neck cancer: interaction between nutrition and mutagen sensitivity. Laryngoscope 1997; 107:765–781.PubMedCrossRefGoogle Scholar
- 63.Cloos J, Spitz MR, Schantz SP, et al. Genetic susceptibility to head and neck squamous cell carcinoma. J Natl Cancer Inst 1996; 88:530–535.PubMedCrossRefGoogle Scholar
- 64.Yu GP, Zhang ZF, Hsu TC, Spitz MR, Schantz SP. Family history of cancer, mutagen sensitivity, and increased risk of head and neck cancer. Cancer Lett 1999; 146:93–101.PubMedCrossRefGoogle Scholar
- 65.Llewellyn CD, Johnson NW, Warnakulasuriya KA. Risk factors for squamous cell carcinoma of the oral cavity in young people—a comprehensive literature review. Oral Oncol 2001; 37:401–418.PubMedCrossRefGoogle Scholar
- 66.La Vecchia C, Negri E. The role of alcohol in oesophageal cancer in non-smokers, and of tobacco in nondrinkers. Int J Cancer 1989; 43:784,785.CrossRefGoogle Scholar
- 67.Talamini R, Franceschi S, Barra S, La Vecchia C. The role of alcohol in oral and pharyngeal cancer in nonsmokers, and of tobacco in non-drinkers. Int J Cancer 1990; 46:391–393.PubMedCrossRefGoogle Scholar
- 68.Mackenzie J, Ah-See K, Thakker N, et al. Increasing incidence of oral cancer amongst young persons: what is the aetiology? ral Oncol 2000; 36:387–389.Google Scholar
- 69.Verschuur HP, Irish JC, O’Sullivan B, Goh C, Gullane PJ, Pintilie M. A matched control study of treatment outcome in young patients with squamous cell carcinoma of the head and neck. Laryngoscope 1999; 109:249–258.PubMedCrossRefGoogle Scholar
- 70.Lipkin A, Miller RH, Woodson GE. Squamous cell carcinoma of the oral cavity, pharynx, and larynx in young adults. Laryngoscope 1985; 95:790–793.PubMedCrossRefGoogle Scholar
- 71.Hart AK, Karakla DW, Pitman KT, Adams JF. Oral and oropharyngeal squamous cell carcinoma in young adults: a report on 13 cases and review of the literature. Otolaryngol Head Neck Surg 1999; 120:828–833.PubMedCrossRefGoogle Scholar
- 72.Khuri FR, Kim ES, Lee JJ, et al. The impact of smoking status, disease stage, and index tumor site on second primary tumor incidence and tumor recurrence in the head and neck retinoid chemoprevention trial. Cancer Epidemiol Biomarkers Prev 2001; 10:823–829.PubMedGoogle Scholar
- 73.Sisk EA, Soltys SG, Zhu S, Fisher SG, Carey TE, Bradford CR. Human papillomavirus and p53 mutational status as prognostic factors in head and neck carcinoma. Head Neck 2002; 24:841–849.PubMedCrossRefGoogle Scholar
- 74.Ritchie JM, Smith EM, Summersgill KF, et al. Human papillomavirus infection as a prognostic factor in carcinomas of the oral cavity and oropharynx. Int J Cancer 2003; 104:336–344.PubMedCrossRefGoogle Scholar
- 75.Brandwein M, Zeitlin J, Nuovo GJ, et al. HPV detection using “hot start” polymerase chain reaction in patients with oral cancer: a clinicopathological study of 64 patients. Mod Pathol 19 1994; 7:720–727Google Scholar
- 76.Haraf DJ, Nodzenski E, Brachman D, et al. Human papilloma virus and p53 in head and neck cancer: clinical correlates and survival. Clin Cancer Res 1996; 2:755–762.PubMedGoogle Scholar
- 77.Paz IB, Cook N, Odom-Maryon T, Xie Y, Wilczynski SP. Human papillomavirus (HPV) in head and neck cancer. An association of HPV 16 with squamous cell carcinoma of Waldeyer’s tonsillar ring. Cancer 1997; 79:595–604.PubMedCrossRefGoogle Scholar
- 78.Balz V, Scheckenbach K, Gotte K, Bockmuhl U, Petersen I, Bier H. Is the p53 inactivation frequency in squamous cell carcinomas of the head and neck underestimated? Analysis of p53 exons 2–11 and human papillomavirus 16/18 E6 transcripts in 123 unselected tumor specimens. Cancer Res 2003; 63:1188–1191.PubMedGoogle Scholar
- 79.Hafkamp HC, Speel EJ, Haesevoets A, et al. A subset of head and neck squamous cell carcinomas exhibits integration of HPV 16/18 DNA and overexpression of p16INK4A and p53 in the absence of mutations in p53 exons 5–8. Int J Cancer 2003; 107:394–400.PubMedCrossRefGoogle Scholar
- 80.Niedobitek G, Pitteroff S, Herbst H, et al. Detection of human papillomavirus type 16 DNA in carcinomas of the palatine tonsil. J Clin Pathol 1990; 43:918–921.PubMedCrossRefGoogle Scholar
- 81.Snijders PJ, Meijer CJ, van den Brule AJ, Schrijnemakers HF, Snow GB, Walboomers JM. Human papillomavirus (HPV) type 16 and 33 E6/E7 region transcripts in tonsillar carcinomas can originate from integrated and episomal HPV DNA. J Gen Virol 1992; 73:2059–2066.PubMedGoogle Scholar
- 82.Wilczynski SP, Lin BT, Xie Y, Paz IB. Detection of human papillomavirus DNA and oncoprotein overexpression are associated with distinct morphological patterns of tonsillar squamous cell carcinoma. Am J Pathol 1998; 152:145–156.PubMedGoogle Scholar
- 83.Mellin H, Friesland S, Lewensohn R, Dalianis T, Munck-Wikland E. Human papillomavirus (HPV) DNA in tonsillar cancer: clinical correlates, risk of relapse, and survival. Int J Cancer 2000; 89:300–304.PubMedCrossRefGoogle Scholar
- 84.Strome SE, Savva A, Brissett AE, et al. Squamous cell carcinoma of the tonsils: a molecular analysis of HPV associations. Clin Cancer Res 2002; 8:1093–1100.PubMedGoogle Scholar
- 85.Klussmann JP, Weissenborn SJ, Wieland U, et al. Human papillomavirus-positive tonsillar carcinomas: a different tumor entity? Med Microbiol Immunol (Berl) 2003; 192:129–132.CrossRefGoogle Scholar
- 86.Schwartz SR, Yueh B, McDougall JK, Daling JR, Schwartz SM. Human papillomavirus infection and survival in oral squamous cell cancer: a population-based study. Otolaryngol Head Neck Surg 2001; 125:1–9.PubMedCrossRefGoogle Scholar
- 87.Ringstrom E, Peters E, Hasegawa M, Posner M, Liu M, Kelsey KT. Human papillomavirus type 16 and squamous cell carcinoma of the head and neck. Clin Cancer Res 2002; 8:3187–3192.PubMedGoogle Scholar
- 88.Braakhuis BJ, Snijders PJ, Keune WJ, et al. Genetic patterns in head and neck cancers that contain or lack transcriptionally active human papillomavirus. J Natl Cancer Inst 2004; 96:998–1006.PubMedCrossRefGoogle Scholar
- 89.Mellin H, Dahlgren L, Munck-Wikland E, et al. Human papillomavirus type 16 is episomal and a high viral load may be correlated to better prognosis in tonsillar cancer. Int J Cancer 2002; 102:152–158.PubMedCrossRefGoogle Scholar
- 90.Klussmann JP, Weissenborn SJ, Wieland U, et al. Prevalence, distribution, and viral load of human papillomavirus 16 DNA in tonsillar carcinomas. Cancer 2001; 92:2875–2884.PubMedCrossRefGoogle Scholar
- 91.Klussmann JP, Gultekin E, Weissenborn SJ, et al. Expression of p16 protein identifies a distinct entity of tonsillar carcinomas associated with human papillomavirus. Am J Pathol 2003; 162:747–753.PubMedGoogle Scholar
- 92.Ha PK, Pai SI, Westra WH, et al. Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity. Clin Cancer Res 2002; 8:1203–1209.PubMedGoogle Scholar
- 93.Steenbergen RD, Hermsen MA, Walboomers JM, et al. Integrated human papillomavirus type 16 and loss of heterozygosity at 11q22 and 18q21 in an oral carcinoma and its derivative cell line. Cancer Res 1995; 55:5465–5471.PubMedGoogle Scholar
- 94.Lindel K, Beer KT, Laissue J, Greiner RH, Aebersold DM. Human papillomavirus positive squamous cell carcinoma of the oropharynx: a radiosensitive subgroup of head and neck carcinoma. Cancer 2001; 92:805–813.PubMedCrossRefGoogle Scholar
- 95.Wiest T, Schwarz E, Enders C, Flechtenmacher C, Bosch FX. Involvement of intact HPV16 E6/E7 gene expression in head and neck cancers with unaltered p53 status and perturbed pRb cell cycle control. Oncogene 2002; 21:1510–1517.PubMedCrossRefGoogle Scholar
- 96.Koskinen WJ, Chen RW, Leivo I, et al. Prevalence and physical status of human papillomavirus in squamous cell carcinomas of the head and neck. Int J Cancer 2003; 107:401–406.PubMedCrossRefGoogle Scholar
- 97.Ke LD, Adler-Storthz K, Mitchell MF, Clayman GL, Chen Z. Expression of human papillomavirus E7 mRNA in human oral and cervical neoplasia and cell lines. Oral Oncol 1999; 35:415–420.PubMedCrossRefGoogle Scholar
- 98.van Houten VM, Snijders PJ, van den Brekel MW, et al. Biological evidence that human papillomaviruses are etiologically involved in a subgroup of head and neck squamous cell carcinomas. Int J Cancer 2001; 93:232–235.PubMedCrossRefGoogle Scholar
- 99.Zumbach K, Kisseljov F, Sacharova O, et al. Antibodies against oncoproteins E6 and E7 of human papillomavirus types 16 and 18 in cervical-carcinoma patients from Russia. Int J Cancer 2000; 85:313–318.PubMedCrossRefGoogle Scholar
- 100.Mork J, Lie AK, Glattre E, et al. Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. N Engl J Med 2001; 344:1125–1131.PubMedCrossRefGoogle Scholar
- 101.Yu MC, Yuan JM. Epidemiology of nasopharyngeal carcinoma. Semin Cancer Biol 2002; 12:421–429.PubMedCrossRefGoogle Scholar
- 102.Nicholls JM, Agathanggelou A, Fung K, Zeng X, Niedobitek G. The association of squamous cell carcinomas of the nasopharynx with Epstein-Barr virus shows geographical variation reminiscent of Burkitt’s lymphoma. J Pathol 1997; 183:164–168.PubMedCrossRefGoogle Scholar
- 103.Akao I, Sato Y, Mukai K, et al. Localization of Epstein-Barr virus in lymph node metastasis with nasopharyngeal carcinoma. Acta Otolaryngol Suppl 1996; 522:86–68.PubMedGoogle Scholar
- 104.Raab-Traub N, Rajadurai P, Flynn K, Lanier AP. Epstein-Barr virus infection in carcinoma of the salivary gland. J Virol 1991; 65:7032–7036.PubMedGoogle Scholar
- 105.zur Hausen H, Schulte-Holthausen H, Klein G, et al. EBV DNA in biopsies of Burkitt tumours and anaplastic carcinomas of the nasopharynx. Nature 1970; 228:1056–1058.PubMedCrossRefGoogle Scholar
- 106.Nam JM, McLaughlin JK, Blot WJ. Cigarette smoking, alcohol, and nasopharyngeal carcinoma: a case-control study among U.S. whites. J Natl Cancer Inst 1992; 84:619–622.PubMedCrossRefGoogle Scholar
- 107.Zhu K, Levine RS, Brann EA, Gnepp DR, Baum MK. A population-based case-control study of the relationship between cigarette smoking and nasopharyngeal cancer (United States). Cancer Causes Control 1995; 6:507–512.PubMedCrossRefGoogle Scholar
- 108.Cheng YJ, Hildesheim A, Hsu MM, et al. Cigarette smoking, alcohol consumption and risk of nasopharyngeal carcinoma in Taiwan. Cancer Causes Control 1999; 10:201–207.PubMedCrossRefGoogle Scholar
- 109.Vaughan TL, Shapiro JA, Burt RD, et al. Nasopharyngeal cancer in a low-risk population: defining risk factors by histological type. Cancer Epidemiol Biomarkers Prev 1996; 5:587–593.PubMedGoogle Scholar
- 110.Goodman M, Morgan RW, Ray R, Malloy CD, Zhao K. Cancer in asbestos-exposed occupational cohorts: a meta-analysis. Cancer Causes Control 1999; 10:453–465.PubMedCrossRefGoogle Scholar
- 111.Browne K, Gee JB. Asbestos exposure and laryngeal cancer. Ann Occup Hyg 2000; 44:239–250.PubMedGoogle Scholar
- 112.Gustavsson P, Jakobsson R, Johansson H, Lewin F, Norell S, Rutkvist LE. Occupational exposures and squamous cell carcinoma of the oral cavity, pharynx, larynx, and oesophagus: a case-control study in Sweden. Occup Environ Med 1998; 55:393–400.PubMedCrossRefGoogle Scholar
- 113.Berrino F, Richiardi L, Boffetta P, et al. Occupation and larynx and hypopharynx cancer: a job-exposure matrix approach in an international case-control study in France, Italy, Spain and Switzerland. Cancer Causes Control 2003; 14:213–223.PubMedCrossRefGoogle Scholar
- 114.Marchand JL, Luce D, Leclerc A, et al. Laryngeal and hypopharyngeal cancer and occupational exposure to asbestos and man-made vitreous fibers: results of a case-control study. Am J Ind Med 2000; 37:581–589.PubMedCrossRefGoogle Scholar
- 115.De Stefani E, Boffetta P, Oreggia F, Ronco A, Kogevinas M, Mendilaharsu M. Occupation and the risk of laryngeal cancer in Uruguay. Am J Ind Med 1998; 33:537–542.PubMedCrossRefGoogle Scholar
- 116.Ahrens W, Jockel KH, Patzak W, Elsner G. Alcohol, smoking, and occupational factors in cancer of the larynx: a case-control study. Am J Ind Med 1991; 20:477–493.PubMedCrossRefGoogle Scholar
- 117.Dietz A, Ramroth H, Urban T, Ahrens W, Becher H. Exposure to cement dust, related occupational groups and laryngeal cancer risk: results of a population based case-control study. Int J Cancer 2004; 108:907–911.PubMedCrossRefGoogle Scholar
- 118.Maier H, Dietz A, Gewelke U, Heller WD. [Occupational exposure to hazardous substances and risk of cancer in the area of the mouth cavity, oropharynx, hypopharynx and larynx. A case-control study]. Laryngorhinootologie 1991; 70:93–98.PubMedGoogle Scholar
- 119.Cauvin JM, Guenel P, Luce D, Brugere J, Leclerc A. Occupational exposure and head and neck carcinoma. Clin Otolaryngol 1990; 15:439–445.PubMedCrossRefGoogle Scholar
- 120.IARC. Wood dust and formaldehyde. IARC Monographs on the Evaluation of the Carcinogenic Risks to Humans 1995; 62:94–215.Google Scholar
- 121.Blot WJ, Chow WH, McLaughlin JK. Wood dust and nasal cancer risk. A review of the evidence from North America. J Occup Environ Med 1997; 39:148–156.PubMedCrossRefGoogle Scholar
- 122.Demers PA, Boffetta P, Kogevinas M, et al. Pooled reanalysis of cancer mortality among five cohorts of workers in wood-related industries. Scand J Work Environ Health 1995; 21:179–190.PubMedGoogle Scholar
- 123.Stellman SD, Demers PA, Colin D, Boffetta P. Cancer mortality and wood dust exposure among participants in the American Cancer Society Cancer Prevention Study-II (CPS-II). Am J Ind Med 1998; 34:229–237.PubMedCrossRefGoogle Scholar
- 124.Mannetje A, Kogevinas M, Luce D, et al. Sinonasal cancer, occupation, and tobacco smoking in European women and men. Am J Ind Med 1999; 36:101–107.PubMedCrossRefGoogle Scholar
- 125.Demers PA, Kogevinas M, Boffetta P, et al. Wood dust and sino-nasal cancer: pooled reanalysis of twelve case-control studies. Am J Ind Med 1995; 28:151–166.PubMedCrossRefGoogle Scholar
- 126.Muscat JE, Wynder EL. Tobacco, alcohol, asbestos, and occupational risk factors for laryngeal cancer. Cancer 1992; 69:2244–2251.PubMedCrossRefGoogle Scholar
- 127.Zagraniski RT, Kelsey JL, Walter SD. Occupational risk factors for laryngeal carcinoma: Connecticut, 1975-1980. Am J Epidemiol 1986; 124:67–76.PubMedGoogle Scholar
- 128.Coble JB, Brown LM, Hayes RB, et al. Sugarcane farming, occupational solvent exposures, and the risk of oral cancer in Puerto Rico. J Occup Environ Med 2003; 45:869–874.PubMedCrossRefGoogle Scholar
- 129.Brown LM, Moradi T, Gridley G, Plato N, Dosemeci M, Fraumeni JF, Jr. Exposures in the painting trades and paint manufacturing industry and risk of cancer among men and women in Sweden. J Occup Environ Med 2002; 44:258–264.PubMedCrossRefGoogle Scholar
- 130.Maier H, Tisch M, Enderle G, Dietz A, Weidauer H. [Occupational exposure to paint, lacquer and solvents, and cancer risk in the area of the upper aero-digestive tract]. HNO 1997; 45:905–908.PubMedCrossRefGoogle Scholar
- 131.Goldberg P, Leclerc A, Luce D, Morcet JF, Brugere J. Laryngeal and hypopharyngeal cancer and occupation: results of a case control-study. Occup Environ Med 1997; 54:477–482.PubMedGoogle Scholar
- 132.Pogoda JM, Preston-Martin S. Solar radiation, lip protection, and lip cancer risk in Los Angeles County women (California, United States). Cancer Causes Control 1996; 7:458–463.PubMedCrossRefGoogle Scholar
- 133.Wiklund K, Holm LE. Trends in cancer risks among Swedish agricultural workers. J Natl Cancer Inst 1986; 77:657–664.PubMedGoogle Scholar
- 134.Dardanoni L, Gafa L, Paterno R, Pavone G. A case-control study on lip cancer risk factors in Ragusa (Sicily). Int J Cancer 1984; 34:335–337.PubMedCrossRefGoogle Scholar
- 135.Perea-Milla Lopez E, Minarro-Del Moral RM, Martinez-Garcia C, et al. Lifestyles, environmental and phenotypic factors associated with lip cancer: a case-control study in southern Spain. Br J Cancer 2003; 88:1702–1707.PubMedCrossRefGoogle Scholar
- 136.Lissowska J, Pilarska A, Pilarski P, et al. Smoking, alcohol, diet, dentition and sexual practices in the epidemiology of oral cancer in Poland. Eur J Cancer Prev 2003; 12:25–33.PubMedCrossRefGoogle Scholar
- 137.Maier H, Tisch M, Kyrberg H, Conradt C, Weidauer H. [Occupational hazardous substance exposure and nutrition. Risk factors for mouth, pharyngeal and laryngeal carcinomas?]. HNO 2002; 50:743–752.PubMedCrossRefGoogle Scholar
- 138.Winn DM, Ziegler RG, Pickle LW, Gridley G, Blot WJ, Hoover RN. Diet in the etiology of oral and pharyngeal cancer among women from the southern United States. Cancer Res 1984; 44:1216–1222.PubMedGoogle Scholar
- 139.Zheng W, Blot WJ, Shu XO, et al. Risk factors for oral and pharyngeal cancer in Shanghai, with emphasis on diet. Cancer Epidemiol Biomarkers Prev 1992; 1:441–448.PubMedGoogle Scholar
- 140.Zheng W, Blot WJ, Diamond EL, et al. Serum micronutrients and the subsequent risk of oral and pharyngeal cancer. Cancer Res 1993; 53:795–798.PubMedGoogle Scholar
- 141.Kucuk O, Pung A, Franke AA, et al. Correlations between mutagen sensitivity and plasma nutrient levels of healthy individuals. Cancer Epidemiol Biomarkers Prev 1995; 4:217–221.PubMedGoogle Scholar
- 142.Brady WE, Mares-Perlman JA, Bowen P, Stacewicz-Sapuntzakis M. Human serum carotenoid concentrations are related to physiologic and lifestyle factors. J Nutr 1996; 126:129–137.PubMedGoogle Scholar
- 143.Ross MA, Crosley LK, Brown KM, et al. Plasma concentrations of carotenoids and antioxidant vitamins in Scottish males: influences of smoking. Eur J Clin Nutr 1995; 49:861–865.PubMedGoogle Scholar
- 144.Faruque MO, Khan MR, Rahman MM, Ahmed F. Relationship between smoking and antioxidant nutrient status. Br J Nutr 1995; 73:625–632.PubMedCrossRefGoogle Scholar
- 145.Kucuk O, Prasad A. Chapter 14: Nutrients, phytochemicals, and squamous cell carcinoma of the head and neck. In: Ensley JF, Gutkind JS, Jacobs JR, Lippman SM, eds. Head and Neck Cancer: Emerging Perspectives: Academic Press; San Diego CA, 2003, pp. 201–211.Google Scholar
- 146.Albanes D, Heinonen OP, Taylor PR, et al. Alpha-Tocopherol and beta-carotene supplements and lung cancer incidence in the alpha-tocopherol, beta-carotene cancer prevention study: effects of base-line characteristics and study compliance. J Natl Cancer Inst 1996; 88:1560–1570.PubMedCrossRefGoogle Scholar
- 147.Gagari E, Kabani S. Adverse effects of mouthwash use. A review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1995; 80:432–439.PubMedCrossRefGoogle Scholar
- 148.Morse DE, Katz RV, Pendrys DG, et al. Mouthwash use and dentures in relation to oral epithelial dysplasia. Oral Oncol 1997; 33:338–343.PubMedCrossRefGoogle Scholar
- 149.Mashberg A, Barsa P, Grossman ML. A study of the relationship between mouthwash use and oral and pharyngeal cancer. J Am Dent Assoc 1985; 110:731–734.PubMedGoogle Scholar
- 150.Wynder EL, Kabat G, Rosenberg S, Levenstein M. Oral cancer and mouthwash use. J Natl Cancer Inst 1983; 70:255–260.PubMedGoogle Scholar
- 151.Elmore JG, Horwitz RI. Oral cancer and mouthwash use: evaluation of the epidemiologic evidence. Otolaryngol Head Neck Surg 1995; 113:253–261.PubMedCrossRefGoogle Scholar
- 152.Young TB, Ford CN, Brandenburg JH. An epidemiologic study of oral cancer in a statewide network. Am J Otolaryngol 1986; 7:200–208.PubMedGoogle Scholar
- 153.Winn DM, Blot WJ, McLaughlin JK, et al. Mouthwash use and oral conditions in the risk of oral and pharyngeal cancer. Cancer Res 1991; 51:3044–3047.PubMedGoogle Scholar
- 154.Blot WJ, Winn DM, Fraumeni JF, Jr. Oral cancer and mouthwash. J Natl Cancer Inst 1983; 70:251–253.PubMedGoogle Scholar
- 155.Winn DM, Diehl SR, Brown LM, et al. Mouthwash in the etiology of oral cancer in Puerto Rico. Cancer Causes Control 2001; 12:419–429.PubMedCrossRefGoogle Scholar
- 156.Bundgaard T, Wildt J, Frydenberg M, Elbrond O, Nielsen JE. Case-control study of squamous cell cancer of the oral cavity in Denmark. Cancer Causes Control 1995; 6:57–67.PubMedCrossRefGoogle Scholar
- 157.Zheng TZ, Boyle P, Hu HF, et al. Dentition, oral hygiene, and risk of oral cancer: a case-control study in Beijing, People’s Republic of China. Cancer Causes Control 1990; 1:235–241.PubMedCrossRefGoogle Scholar
- 158.Marshall JR, Graham S, Haughey BP, et al. Smoking, alcohol, dentition and diet in the epidemiology of oral cancer. Eur J Cancer B Oral Oncol 1992; 28B:9–15.PubMedCrossRefGoogle Scholar
- 159.Franco EL, Kowalski LP, Oliveira BV, et al. Risk factors for oral cancer in Brazil: a case-control study. Int J Cancer 1989; 43:992–1000.PubMedCrossRefGoogle Scholar
- 160.Maier H, Zoller J, Herrmann A, Kreiss M, Heller WD. Dental status and oral hygiene in patients with head and neck cancer. Otolaryngol Head Neck Surg 1993; 108:655–661.PubMedGoogle Scholar
- 161.Moreno-Lopez LA, Esparza-Gomez GC, Gonzalez-Navarro A, Cerero-Lapiedra R, Gonzalez-Hernandez MJ, Dominguez-Rojas V. Risk of oral cancer associated with tobacco smoking, alcohol consumption and oral hygiene: a case-control study in Madrid, Spain. Oral Oncol 2000; 36:170–174.PubMedCrossRefGoogle Scholar
- 162.Talamini R, Vaccarella S, Barbone F, et al. Oral hygiene, dentition, sexual habits and risk of oral cancer. Br J Cancer 2000; 83:1238–1242.PubMedCrossRefGoogle Scholar
- 163.Ward PH, Hanson DG. Reflux as an etiological factor of carcinoma of the laryngopharynx. Laryngoscope 1988; 98:1195–1199.PubMedGoogle Scholar
- 164.Morrison MD. Is chronic gastroesophageal reflux a causative factor in glottic carcinoma? Otolaryngol Head Neck Surg 1988; 99:370–373.PubMedGoogle Scholar
- 165.Koufman JA. The otolaryngologic manifestations of gastroesophageal reflux disease (GERD): a clinical investigation of 225 patients using ambulatory 24-hour pH monitoring and an experimental investigation of the role of acid and pepsin in the development of laryngeal injury. Laryngoscope 1991; 101:1–78.PubMedCrossRefGoogle Scholar
- 166.Biacabe B, Gleich LL, Laccourreye O, Hartl DM, Bouchoucha M, Brasnu D. Silent gastroesophageal reflux disease in patients with pharyngolaryngeal cancer: further results. Head Neck 1998; 20:510–514.PubMedCrossRefGoogle Scholar
- 167.El-Serag HB, Hepworth EJ, Lee P, Sonnenberg A. Gastroesophageal reflux disease is a risk factor for laryngeal and pharyngeal cancer. Am J Gastroenterol 2001; 96:2013–2018.PubMedCrossRefGoogle Scholar
- 168.Singh B, Sabin S, Rofim O, Shaha A, Har-El G, Lucente FE. Alterations in head and neck cancer occurring in HIV-infected patients—results of a pilot, longitudinal, prospective study. Acta Oncol 1999; 38:1047–1050.PubMedCrossRefGoogle Scholar
- 169.Barry B, Gehanno P. [Squamous cell carcinoma of the ENT organs in the course of the HIV infection]. Ann Otolaryngol Chir Cervicofac 1999; 116:149–153.PubMedGoogle Scholar
- 170.Frisch M, Biggar RJ, Goedert JJ. Human papillomavirus-associated cancers in patients with human immunodeficiency virus infection and acquired immunodeficiency syndrome. J Natl Cancer Inst 2000; 92:1500–1510.PubMedCrossRefGoogle Scholar
- 171.Bradford CR, Hoffman HT, Wolf GT, Carey TE, Baker SR, McClatchey KD. Squamous carcinoma of the head and neck in organ transplant recipients: possible role of oncogenic viruses. Laryngoscope 1990; 100:190–194.PubMedCrossRefGoogle Scholar
- 172.Duvoux C, Delacroix I, Richardet JP, et al. Increased incidence of oropharyngeal squamous cell carcinomas after liver transplantation for alcoholic cirrhosis. Transplantation 1999; 67:418–421.PubMedCrossRefGoogle Scholar
- 173.Zhang L, Epstein JB, Poh CF, et al. Comparison of HPV infection, p53 mutation and allelic losses in posttransplant and non-posttransplant oral squamous cell carcinomas. J Oral Pathol Med 2002; 31:134–141.PubMedCrossRefGoogle Scholar
- 174.Silverman S, Jr., Bahl S. Oral lichen planus update: clinical characteristics, treatment responses, and malignant transformation. Am J Dent 1997; 10:259–263.PubMedGoogle Scholar
- 175.van der Meij EH, Schepman KP, Smeele LE, van der Wal JE, Bezemer PD, van der Waal I. A review of the recent literature regarding malignant transformation of oral lichen planus. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 1999; 88:307–310.PubMedCrossRefGoogle Scholar
- 176.Hietanen J, Paasonen MR, Kuhlefelt M, Malmstrom M. A retrospective study of oral lichen planus patients with concurrent or subsequent development of malignancy. Oral Oncol 1999; 35:278–282.PubMedCrossRefGoogle Scholar
- 177.Epstein JB, Wan LS, Gorsky M, Zhang L. Oral lichen planus: progress in understanding its malignant potential and the implications for clinical management. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2003; 96:32–37.PubMedCrossRefGoogle Scholar
- 178.Zhang L, Cheng X, Li Y, et al. High frequency of allelic loss in dysplastic lichenoid lesions. Lab Invest 2000; 80:233–237.PubMedGoogle Scholar
- 179.Zhang L, Michelsen C, Cheng X, Zeng T, Priddy R, Rosin MP. Molecular analysis of oral lichen planus. A premalignant lesion? Am J Pathol 1997; 151:323–327.PubMedGoogle Scholar
- 180.Foulkes WD, Brunet JS, Kowalski LP, Narod SA, Franco EL. Family history of cancer is a risk factor for squamous cell carcinoma of the head and neck in Brazil: a case-control study. Int J Cancer 1995; 63:769–773.PubMedCrossRefGoogle Scholar
- 181.Brown LM, Gridley G, Diehl SR, et al. Family cancer history and susceptibility to oral carcinoma in Puerto Rico. Cancer 2001; 92:2102–2108.PubMedCrossRefGoogle Scholar
- 182.Foulkes WD, Brunet JS, Sieh W, Black MJ, Shenouda G, Narod SA. Familial risks of squamous cell carcinoma of the head and neck: retrospective case-control study. BMJ 1996; 313:716–721.PubMedGoogle Scholar
- 183.Copper MP, Jovanovic A, Nauta JJ, et al. Role of genetic factors in the etiology of squamous cell carcinoma of the head and neck. Arch Otolaryngol Head Neck Surg 1995; 121:157–160.PubMedGoogle Scholar
- 184.Mork J, Moller B, Glattre E. Familial risk in head and neck squamous cell carcinoma diagnosed before the age of 45: a population-based study. Oral Oncol 1999; 35:360–367.PubMedCrossRefGoogle Scholar
- 185.Goldstein AM, Blot WJ, Greenberg RS, et al. Familial risk in oral and pharyngeal cancer. Eur J Cancer B Oral Oncol 1994; 30B(5):319–22.PubMedCrossRefGoogle Scholar
- 186.Li X, Hemminki K. Familial upper aerodigestive tract cancers: incidence trends, familial clustering and subsequent cancers. Oral Oncol 2003; 39:232–239.PubMedCrossRefGoogle Scholar
- 187.Hemminki K, Li X. Familial risks of cancer as a guide to gene identification and mode of inheritance. Int J Cancer 2004; 110:291–294.PubMedCrossRefGoogle Scholar
- 188.Bongers V, Braakhuis BJ, Tobi H, Lubsen H, Snow GB. The relation between cancer incidence among relatives and the occurrence of multiple primary carcinomas following head and neck cancer. Cancer Epidemiol Biomarkers Prev 1996; 5:595–598.PubMedGoogle Scholar
- 189.Dong YJ, Peng TK, Yin SJ. Expression and activities of class IV alcohol dehydrogenase and class III aldehyde dehydrogenase in human mouth. Alcohol 1996; 13:257–262.PubMedCrossRefGoogle Scholar
- 190.Bosron WF, Li TK. Genetic polymorphism of human liver alcohol and aldehyde dehydrogenases, and their relationship to alcohol metabolism and alcoholism. Hepatology 1986; 6:502–510.PubMedCrossRefGoogle Scholar
- 191.Olshan AF, Weissler MC, Watson MA, Bell DA. Risk of head and neck cancer and the alcohol dehydrogenase 3 genotype. Carcinogenesis 2001; 22:57–61.PubMedCrossRefGoogle Scholar
- 192.Zavras AI, Wu T, Laskaris G, et al. Interaction between a single nucleotide polymorphism in the alcohol dehydrogenase 3 gene, alcohol consumption and oral cancer risk. Int J Cancer 2002; 97:526–530.PubMedCrossRefGoogle Scholar
- 193.Geisler SA, Olshan AF. GSTM1, GSTT1, and the risk of squamous cell carcinoma of the head and neck: a mini-HuGE review. Am J Epidemiol 2001; 154:95–105.PubMedCrossRefGoogle Scholar
- 194.Cheng L, Sturgis EM, Eicher SA, Char D, Spitz MR, Wei Q. Glutathione-S-transferase polymorphisms and risk of squamous-cell carcinoma of the head and neck. Int J Cancer 1999; 84:220–224.PubMedCrossRefGoogle Scholar
- 195.Olshan AF, Weissler MC, Watson MA, Bell DA. GSTM1, GSTT1, GSTP1, CYP1A1, and NAT1 polymorphisms, tobacco use, and the risk of head and neck cancer. Cancer Epidemiol Biomarkers Prev 2000; 9:185–191.PubMedGoogle Scholar
- 196.Kutler DI, Auerbach AD, Satagopan J, et al. High incidence of head and neck squamous cell carcinoma in patients with Fanconi anemia. Arch Otolaryngol Head Neck Surg 2003; 129:106–112.PubMedCrossRefGoogle Scholar
- 197.Alter BP. Cancer in Fanconi anemia, 1927-2001. Cancer 2003; 97:425–440.PubMedCrossRefGoogle Scholar
- 198.Rosenberg PS, Greene MH, Alter BP. Cancer incidence in persons with Fanconi anemia. Blood 2003; 101:822–826.PubMedCrossRefGoogle Scholar
- 199.Kutler DI, Wreesmann VB, Goberdhan A, et al. Human papillomavirus DNA and p53 polymorphisms in squamous cell carcinomas from Fanconi anemia patients. J Natl Cancer Inst 2003; 95:1718–1721.PubMedGoogle Scholar
- 200.Lowy DR, Gillison ML. A new link between Fanconi anemia and human papillomavirus-associated malignancies. J Natl Cancer Inst 2003; 95:1648–1650.PubMedGoogle Scholar
- 201.Kutler DI, Singh B, Satagopan J, et al. A 20-year perspective on the International Fanconi Anemia Registry (IFAR). Blood 2003; 101:1249–1256.PubMedCrossRefGoogle Scholar
- 202.Singh B, Wreesmann VB, Phister, et al. Chromosomal aberrations in patients with head and neck squamous cell carcinoma do not vary based on severity of tobacco/alcohol exposure. BMC Genet 2002; 3:22.PubMedCrossRefGoogle Scholar
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