Abstract
Only relatively recently has programmed cell death (PCD) been fully appreciated as a central component of development and disease. Removal of damaged cells represents one of the most important defenses our body has to prevent pathology, and abnormal removal of cells has been observed in a number of degenerative diseases. In this review, we emphasize the importance of cell death during development, with a brief excursion at the end to examine neurodegeneration. The fruitfly Drosophila has been at the center of a number of important discoveries regarding development and signal transduction, so it is perhaps surprising that it has been a relatively late entrant into the world of programmed cell death. However, flies have been making up for lost time.
Keywords
Programme Cell Death Nurse Cell Morphogenetic Furrow Embryonic Epidermis Midline CellPreview
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References
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