Cytokines in Allogeneic Stem Cell Mobilization

  • Ravi Vij
  • Randy Brown
  • John F. DiPersio
Part of the Current Clinical Oncology book series (CCO)


Since the mid-1990s when the first trials of cytokine-mobilized allogeneic peripheral blood stem cell (allo-PBSC) transplants appeared in the literature, there has been a steady increase in the use of allo-PBSC in lieu of bone marrow as a source of stem cells. For normal donors, the collection of PBSC by apheresis techniques is a feasible alternative to undergoing marrow harvest with anesthesia and avoids the potential morbidity associated with marrow collection. This trend has further accelerated with the publication of a randomized trial suggesting a superior survival for patients where peripheral blood was used as a source of stem cells over the use of bone marrow (1).


Stem Cell Acute Myeloid Leukemia Hematopoietic Progenitor Normal Donor Hematopoietic Progenitor Cell 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Ravi Vij
  • Randy Brown
  • John F. DiPersio

There are no affiliations available

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