Cryptococcus neoformans

  • Vassil St. Georgiev
Part of the Infectious Disease book series (ID)


Cryptococcus neoformans is a yeast-like fungus that is pathogenic to both animals and man. It was first isolated in 1894 by Busse (1) from a patient with osteomyelitis of the tibia. The fungus is a saprophitic organism that can be found in soil, on a variety of fruits, as well as in close association with pigeon nests (2,3). There are two varieties of C. neoformans: C. neoformans var. neoformans and C. neoformans var. gattii. Each of these varieties, in turn, has two serotypes: A and D for var. neoformans, and B and C for var. gattii. In addition, there have been reports of human infections caused by two other Cryptococcus species: C. albidus and C. laurentii.


Acquire Immunodeficiency Syndrome Cryptococcus Neoformans Cryptococcal Meningitis Oral Fluconazole Cryptococcal Infection 
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Copyright information

© Springer Science+Business Media New York 2003

Authors and Affiliations

  • Vassil St. Georgiev
    • 1
  1. 1.National Institute of Allergy and Infectious DiseasesNational Institutes of HealthBethesdaUSA

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