Genetics of Tumoral Calcinosis

  • Kandaswamy Jayaraj
  • Kenneth Lyles


Tumoral calcinosis is a condition characterized by ectopic periarticular calcifications without the involvement of visceral organs. Five salient features of tumoral calcinosis are:
  1. 1.

    elevated serum phosphorus concentration;

  2. 2.

    elevated serum 1,25 dihydroxy vitamin D (calcitriol) concentration;

  3. 3.

    elevated renal tubular phosphate reabsorbtion;

  4. 4.

    ectopic calcifications; and

  5. 5.

    characteristic dental abnormalities.



Tumoral Calcinosis Calcium Phosphorus Ectopic Calcification Autosomal Dominant Mode Angioid Streak 
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© Springer Science+Business Media New York 2000

Authors and Affiliations

  • Kandaswamy Jayaraj
  • Kenneth Lyles

There are no affiliations available

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