Cloning the Mammoth: A Complicated Task or Just a Dream?

  • Pasqualino LoiEmail author
  • Joseph SaragustyEmail author
  • Grazyna Ptak
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 753)


Recently there has been growing interest in applying the most advanced embryological tools, particularly cloning, to bring extinct species back to life, with a particular focus on the woolly mammoth (Mammuthus primigenius). Mammoth’s bodies found in the permafrost are relatively well preserved, with identifiable nuclei in their tissues. The purpose of this chapter is to review the literature published on the topic, and to present the strategies potentially suitable for a mammoth cloning project, with a frank assessment of their feasibility and the ethical issues involved.


Somatic cell nuclear transfer (SCNT) Cloning Mammoth Elephant 



The research leading to these results received funding from the European Research Council under the European Community Seventh Framework Programme (FP7/ 2007-2013)/ERC grant agreement no 210103 to GP, and PRIN 2007, no 2007MY2M92 to GP. PL acknowledges the support of the EU FP7-KBBE -2009-3 Programme, project no 244356 (NextGene) and PRIN MIUR founding (project no 2009JE3CHM). Funds from the Bank Foundation Tercas (Teramo, Italy) and funds from project “Genhome”, Miur/Firb are acknowledged. The authors are grateful to the Japanese Academy for the permit to reproduce figures published by Kato et al., on Proc. Jpn. Acad. Ser B., Phys Biol Sci. 2009; 85(7):240–7.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of Comparative Biomedical SciencesUniversity of TeramoTeramoItaly
  2. 2.Department of Reproduction ManagementLeibniz Institute for Zoo and Wildlife ResearchBerlinGermany

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