Parathyroid

  • A. J. Coakley
  • C. P. Wells
Chapter

Abstract

Hyperparathyroidism is the disease state associated with overproduction of parathormone (PTH), the biologically active hormone of the parathyroids. While some patients with hyperparathyroidism are managed medically, the only curative treatment is removal of the abnormal gland or glands.

Keywords

Thyroid Nodule Parathyroid Gland Primary Hyperparathyroidism Secondary Hyperparathyroidism Parathyroid Adenoma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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References

  1. 1.
    Coakley, A.J. (1995) Parathyroid imaging. Nucl. Med. Commun., 16, 522–33.PubMedCrossRefGoogle Scholar
  2. 2.
    Ferlin, G., Borsato, N., Camerani, M. et al. (1983) New perspectives in localising enlarged parathyroids by technetium-thallium subtraction scan. J. Nucl. Med., 24, 438–41.PubMedGoogle Scholar
  3. 3.
    Fogelman, I., McKillop, J.H., Bessent, R.G. et al. (1984) Successful localisation of parathyroid adenomata by thallium-201 and technetium-99m subtraction scintigraphy: description of an improved technique. Eur. J. Nucl. Med., 9, 545–7.PubMedCrossRefGoogle Scholar
  4. 4.
    Sandrock, D., Dunham, R.G. and Neumann, R.D. (1990) Simultaneous dual energy acquisition for 201T1/ 9mTc parathyroid subtraction scintigraphy: physical and physiological considerations. Nucl. Med. Commun., 11C, 503–10.CrossRefGoogle Scholar
  5. 5.
    Coakley, A.J., Kettle, A.G., Wells, C.P., O’Doherty, M.J. and Collins, R.E.C. (1989) 99mTc-sestamibi new agent for parathyroid imaging. Nucl. Med. Commun., 10, 791–4.PubMedCrossRefGoogle Scholar
  6. 6.
    O’Doherty, M.J., Kettle, A.G., Wells, P.C., Collins, R.E.C. and Coakley, A.J. (1992) Parathyroid imaging with technetium-99m-sestamibi: preoperative localisation and tissue uptake studies. J. Nucl. Med., 33, 313–18.PubMedGoogle Scholar
  7. 7.
    Geatti, O., Shapiro, B., Orsolon, P.G. et al. (1994) Localization of parathyroid enlargement: experience with Tc-99m MIBI and thallium-201 scintigraphy, ultrasonography and computerised tomography. Eur. J. Nucl. Med., 21, 17–22.PubMedCrossRefGoogle Scholar
  8. 8.
    Taillefer, R., Boucher, Y., Potvin, C. et al. (1992) Detection and localization of parathyroid adenomas in patients with hyperparathyroidism using a single radionuclide imaging procedure with technetium-99m-sestamibi (double-phase study). J. Nucl. Med., 33, 1801–7.PubMedGoogle Scholar
  9. 9.
    McBiles, M., Lambert, A.T., Cote, M.G. et al (1995) Sestamibi parathyroid imaging. Semin. Nucl. Med., XXV, no 3, 221–34.Google Scholar
  10. 10.
    Chen, C.C., Skarulis, M.C., Fraker, D.L. et al. (1995) Technetium-99m-sestamibi imaging before reoperation for primary hyperparathyroidism. J. Nucl. Med., 36(12), 2186–91.PubMedGoogle Scholar
  11. 11.
    Price, D.C. (1993) Radioisotopic evaluation of the thyroid and the parathyroids (review). Radiol. Clin. North Am., 31(5), 991–1015.PubMedGoogle Scholar
  12. 12.
    Sandrock, D., Merino, M.J., Norton, J.A. and Neumann, R.D. (1990) Parathyroid imaging by Tc/Tl scintigraphy. Eur. J. Nucl. Med., 16, 607–13.PubMedCrossRefGoogle Scholar
  13. 13.
    Bugis, S.P., Berno, E., Rusnak, C.H. et al. (1995) Technetium-99m-sestamibi scanning before initial neck exploration in patients with primary hyperparathyroidism. Eur. Arch. Otol. Rhinol. Laryngol., 252(3), 149–52.Google Scholar
  14. 14.
    Caixas, A., Berna, L., Piera, J. et al. (1995) Utility of 99mTc-sestamibi scintigraphy as a first line imaging procedure in the pre-operation evaluation of hyperparathyroidism. Clin. Endocrinol, 43(5), 525–30.CrossRefGoogle Scholar
  15. 15.
    Giordano, A., Meduri, G. and Marozzi, P. (1996) Parathyroid imaging with Tc99m-tetrofosmin. Nucl. Med. Commun., 17(8), 706–10.PubMedCrossRefGoogle Scholar
  16. 16.
    Neumann, D.R., Esselstyn, C.B., Jr, MacIntyre, W.J. et al. (1994) Primary hyperparathyroidism: preoperative parathyroid imaging with regional body FDG PET. Radiology, 192(2), 509–12.PubMedGoogle Scholar
  17. 17.
    Sisson, J.C., Thompson, N.W., Ackerman, R.J. et al (1994) Use of 2-(F-18)-Flouro-2-deoxy-D-glucose PET to locate parathyroid adenomas in primary hyperparathyroidism. Radiology, 192, 280.PubMedGoogle Scholar
  18. 18.
    Melon, P., Luxen, A., Hamoir, E. et al. (1995) Flourine-18-flourodeoxyglucose positron emission tomography for pre-operative parathyroid imaging in primary hyperparathyroidism. Eur. J. Nucl. Med., 22(6), 556–8.PubMedCrossRefGoogle Scholar
  19. 19.
    Hellman, P., Ahlstrom, H., Bergstrom, M. et al. (1994) Positron emission tomography with 11C-methionine in hyperparathyroidism. Surgery, 116(6), 974–81.PubMedGoogle Scholar
  20. 20.
    Edis, A.J., Sheedy, P.F., Beahrs, O.H. and van Heerden, J.A. (1978) Results of re-operation for hyperparathyroidism, with evaluation of preoperative localisation studies. Surgery, 84, 384–93.PubMedGoogle Scholar
  21. 21.
    Consensus Development Conference Panel (1991) Diagnosis and management of asymptomatic primary hyperparathyroidism: consensus development conference statement. Ann. Intern. Med., 114(7), 593–7.CrossRefGoogle Scholar
  22. 22.
    Wei, J.P. and Burke, G.J. (1995) Analysis of savings in operative time for primary hyperparathyroidism using localization with technetium 99m sestamibi scan. Am.J. Surg., 170(5), 488–91.PubMedCrossRefGoogle Scholar
  23. 23.
    Davis, R.K., Hoffmann, J., Dart, D. et al. (1990) Unilateral parathyroidectomy. Otolaryngol. Head Neck Surg., 102, 635–8.PubMedGoogle Scholar
  24. 24.
    Miller, D.L. (1991) Preoperative localization and interventional treatment of parathyroid tumours: when and how? World J. Surg., 15, 706–15.PubMedCrossRefGoogle Scholar

Further Reading

  1. Parathyroid imaging (review). Radiol. Clin. North Am., 1993, 31(5), 967–1028. A comprehensive series of review articles on techniques for parathyroid imagingGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1998

Authors and Affiliations

  • A. J. Coakley
  • C. P. Wells

There are no affiliations available

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