Purine and Pyrimidine Metabolism in Man VII pp 223-226 | Cite as
Serum Urate and Uric Acid Excretion
Abstract
In the course of an epidemiological survey, the following laboratory tests were performed on morning urine and blood specimens obtained from fasting patients seen during a five-month period in the Renzetti Hospital of Lanciano (Chieti): serum uric acid (S.U.A.) (1), serum creatinine (S.CR.) (2), serum total cholesterol (S.CH.) (3), serum triglycerides (S.T.)(1), serum glucose (S.G.) (4), urine uric acid (U.U.A.) (1) and urine creatinine (U.CR.) (2) concentrations. All assays were performed using an automated analyzer (Monarch -Instrumentation Laboratory -). Age, sex and department of admission were also recorded. To quantify renal excretion of urate, uric acid excretion per deciliter of glomerular filtrate (ER) (5) and fractional excretion of uric acid (FE) (urate clearance × 100 / creatinine clearance) were employed in order to avoid problems inherent in a 24-hours urine collection and to correct the excretion rate for differences in body size.
Keywords
Uric Acid Serum Uric Acid Fractional Excretion Serum Total Cholesterol Serum UratePreview
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References
- 1).K. Tamaoku, Y. Murao, K. Akiura. Anal.Chim.Acta, 32:485 (1971)Google Scholar
- 2).J.C.H. Cook, Clin.Chim.Acta, 32:485 (1971)PubMedCrossRefGoogle Scholar
- 3).R. Friedman et al. Clin.Chem. 26: 4 (1980)Google Scholar
- 4).P. Sharp. Clin.Chim.Acta, 40:115 (1972)PubMedCrossRefGoogle Scholar
- 5).P.A. Simkin, P.L. Hoover, C.S. Paxon and W.F. Wilson Ann.Int.Med. 91:44 (1979)PubMedCrossRefGoogle Scholar
- 6).L.A. Healy, A.P. Hall. Bull.Reum.Dis. 20:600 (1970)Google Scholar
- 7).S.L. Wallace. Arthritis Rheum. 18:721 (1975)PubMedCrossRefGoogle Scholar
- 8).J. Zalokar, J. Lellouch, J.R. Claude and D. Kuntz J. Chron. Dis. 25:305 (1972)PubMedCrossRefGoogle Scholar
- 9).R.E. Rieselback, T.H. Steele. Am.J. Med. 56:665 (1974)CrossRefGoogle Scholar