Key Features of Copper versus Molybdenum Metabolism Models in Humans

  • Judith R. TurnlundEmail author
  • Katherine H. Thompson
  • Karen C. Scott
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 445)


Copper and molybdenum are essential nutrients for humans. Both trace elements are required in the diet in small amounts, are toxic in excess, and body stores are low. But there are major differences in their metabolism. Metabolic studies were conducted in the human nutrition suite of the Western Human Nutrition Research Center. Young men were confined to the unit for 2 to 90 days in studies of copper metabolism and for 120 days for studies of molybdenum metabolism. Stable isotopes were used as tracers to follow the metabolic fate of these elements. 65Cu was administered orally and intravenously in the copper studies. 100Mo was administered orally and 97Mo was administered intravenously in the molybdenum studies.


Stable Isotope Thermal Ionization Mass Spectrometry Copper Deficiency Lysyl Oxidase Copper Metabolism 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • Judith R. Turnlund
    • 1
    Email author
  • Katherine H. Thompson
    • 2
  • Karen C. Scott
    • 3
  1. 1.USDA/ARSWestern Human Nutrition Research CenterPresidio of San FranciscoUSA
  2. 2.Chemistry DepartmentThe University of British ColumbiaVancouverCanada
  3. 3.Department of Small Animal Clinical SciencesUniversity of FloridaGainesvilleUSA

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