Why do Some Parasitic Nematodes Secrete Acetylcholinesterase (ACHE)?

  • David. I. Pritchard
  • Chris Jagger
  • Chris Green
  • Ken Lowe


While the expression and secretion of AChE by some parasitic nematodes is well documented (figure 1), the true biological significance(s) of this process remains speculative. Parasite-protective/beneficial roles have been suggested (1), for the following reasons. AChE has the potential to:
  1. i.

    modulate intestinal peristalsis, by destroying host acetylcholine (ACh), thus providing the parasite with a biochemical holdfast. (AChE may not, in fact, be involved (10) in this process.).



Parasitic Nematode Chronic Nicotine Intestinal Peristalsis Chronic Nicotine Treatment Peripheral Blood Lympho 
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Copyright information

© Springer Science+Business Media New York 1998

Authors and Affiliations

  • David. I. Pritchard
    • 1
  • Chris Jagger
    • 1
  • Chris Green
    • 1
  • Ken Lowe
    • 1
  1. 1.School of Biological SciencesUniversity of NottinghamNottinghamEngland

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