Abstract
As with other solid-organ (kidney, liver, heart) recipients, the number of pancreas recipients with 10-year graft function and beyond is steadily increasing. These recipients enjoy long-term normoglycemic metabolism without the need for multiple daily plasma glucose measurements and insulin injections. As shown in chapter 16, they also benefit from the positive effects of long-term pancreas graft function on the secondary complications of diabetes. Long-term pancreas graft function, therefore, not only improves quality of life (see chapter 17) but also markedly reduces the morbidity and mortality traditionally associated with type 1 diabetes mellitus and its secondary complications. Recipients with long-term function are also a constant reminder that a pancreas transplant, despite numerous improvements in the treatment of diabetes mellitus (see chapter 3), remains the only treatment that normalizes glucose metabolism for as long as the graft functions.
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Gruessner, R.W.G., Gruessner, A.C. (2004). Long-Term Pancreas Graft Function. In: Gruessner, R.W.G., Sutherland, D.E.R. (eds) Transplantation of the Pancreas. Springer, New York, NY. https://doi.org/10.1007/978-1-4757-4371-5_18
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DOI: https://doi.org/10.1007/978-1-4757-4371-5_18
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