The Use of High Pressure Liquid Chromatography to Monitor Nucleotide Levels in Cells
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High pressure liquid chromatography has proved to be a valuable tool in measuring the nucleotide levels in cell extracts (1, 2). The analyses are accomplished with high speed, sensitivity, resolution and accuracy. A decided advantage of this technique is that the major naturally occurring nucleotides can be monitored at one time concurrently with nucleotides of purine and pyrimidine analogs.
KeywordsHigh Pressure Liquid Chromatography Adenine Nucleotide Anion Exchange Resin Purine Analog Pyrimidine Analog
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