Taurine, Cysteinesulfinic Acid Decarboxylase and Glutamic Acid in Brain

  • David K. Rassin
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 139)


Despite the intensive studies of many investigators the role of taurine in mammals, other than as a component of taurocholate, is still unknown (2,3,11). The difficulty in assigning a function to taurine results from the large number of organs, actions and conditions with which the compound has been associated, such as neurotransmission (18,29), epilepsy (46,47), development (6,42), nutrition (30), retinal function (23), feline blindness (10,36), mongolism (8), adrenal function (21), cardiac function (9) and others. In addition, specific pharmacologic agonists and antagonists have not been identified, and pathologic changes, other than feline blindness, have not been associated with taurine deficiency or excess. Thus, conclusions cannot be made as yet concerning the function of taurine, and discussions of the importance of this compound still depend upon extrapolation from the descriptive data that are currently available.


Glutamic Acid Glutamic Acid Decarboxylase Kainic Acid Cysteic Acid Chick Brain 
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Copyright information

© Plenum Press, New York 1982

Authors and Affiliations

  • David K. Rassin
    • 1
  1. 1.Division of Developmental Nutrition and Metabolism Department of PediatricsUniversity of Texas Medical BranchGalvestonUSA

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