Recent Advances and Applications of Freeze-Drying Technology

  • D. Greiff
  • T. W. G. Rowe
Chapter
Part of the Advances in Cryogenic Engineering book series (ACRE, volume 21)

Abstract

Despite the advances which have been made during the past thirty years, freeze-drying continues to be more of an art than a science. Although the value of the material processed annually must be on the order of hundreds of millions of dollars, the process of freeze-drying is still greatly underresearched. Lacking especially is a completely satisfactory unified body of theory which would enable a protocol to be drawn up prior to processing on the basis of a few known properties or parameters of the material to be dried. In spite of these restraints, there exist excellent techniques of instrumentation and process control [1] and powerful statistical methods and mathematical models to predict the shelf-life of freeze-dried material [2,3]. Although these studies enable the processor to work on a firm empirical basis, unfortunately they are still widely ignored or misunderstood.

Keywords

Influenza Virus Human Serum Albumin Measle Virus Evaporative Cool Product Temperature 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Springer Science+Business Media New York 1960

Authors and Affiliations

  • D. Greiff
    • 1
  • T. W. G. Rowe
    • 1
  1. 1.The Medical College of WisconsinMilwaukeeUSA

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