Nephrolithiasis Associated with Intestinal Disease

  • J. W. Dobbins
Conference paper

Abstract

It has been noted since the 1960∲s that there is an increased incidence of nephrolithiasis in patients with idiopathic inflammatory bowel disease and in individuals who have undergone jejuno-ileal bypass for obesity1−14. In patients with inflammatory bowel disease, prior surgical treatment increases the risk of nephrolithiasis7,9,10. The incidence of nephrolithiasis in patients with Crohn’s disease who have undergone an ileal resection is approximately 10%. The large majority of these stones, when analyzed, are composed of calcium oxalate. The incidence of nephrolithiasis in patients with ulcerative colitis who have undergone an ileostomy is also approximately 10%. Uric acid stones, however, make up a significant proportion of the calculi in these patients1−3. The incidence of nephrolithiasis in patients who have undergone jejuno-ileal bypass for obesity is 20% or more.

Keywords

Bile Acid Calcium Oxalate Medium Chain Fatty Acid Uric Acid Stone Urinary Abnormality 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
This is a preview of subscription content, log in to check access.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    A. W. Badenoch, Br. J. Urol. 32:374 (1960).PubMedCrossRefGoogle Scholar
  2. 2.
    R. I. Breuer, E. A. Gelzayd, and J. K. Kirsner, Gut 11:314 (1970).PubMedCrossRefGoogle Scholar
  3. 3.
    J. J. Deren, J. G. Porush, M. F. Levit, and M. T. Khilnani, Ann. Intern. Med. 56:843 (1962).PubMedGoogle Scholar
  4. 4.
    S. S. Dickstein and B. Frame, Surg. Gyn. Obst. 136:259 (1973).Google Scholar
  5. 5.
    R. H. Dowling, G. A. Rose, and D. J. Sutor, Lancet 1:1103 (1971).PubMedCrossRefGoogle Scholar
  6. 6.
    E. Fikri and R. R. Cassella, Ann. Surg. 179:460 (1974)PubMedCrossRefGoogle Scholar
  7. 7.
    E. A. Gelzayd, R. I. Breuer, and J. B. Kirsner, Am. J. Dig. Dis. 13:1027 (1968).PubMedCrossRefGoogle Scholar
  8. 8.
    J. G. Gregory, E. B. Starkloff, K. Miyai, and H. Schoenberg, J. Urol. 1 13:521 (1975).Google Scholar
  9. 9.
    M. S. Grossman and F. W. Nugent, Am. J. Dig. Dis. 12:491 (1967).PubMedCrossRefGoogle Scholar
  10. 10.
    Z. Maratka and J. Nedbal, Gut 5:214 (1964).PubMedCrossRefGoogle Scholar
  11. 11.
    J. P. O’Leary, W. C. Thomas and E. R. Woodward, Am. J. Surg. 127:142 (1974).PubMedCrossRefGoogle Scholar
  12. 12.
    K. Dharmsathaphorn, D. H. Freeman, H. J. Binder, and J. D. Dobbins, Dig. Dis. Sci. 17:401 (1982).CrossRefGoogle Scholar
  13. 13.
    E. Hylander, S. Jarnum, and I. Frandsen, Scand. J. Gastroenterol. 14:475 (1979).PubMedGoogle Scholar
  14. 14.
    C. P. Bambach, W. G. Robertson, M. Peacock, and G. L. Hill, Gut 22:257 (1981).PubMedCrossRefGoogle Scholar
  15. 15.
    L. H. Smith, P. G. Werness, and D. M. Wilson, in: “Oxalate in Human Biochemistry and Clinical Pathology”, G. A. Rose, W. G. Robertson, and R. W. E. Watts, eds., Wellcome Foundation, London (1979).Google Scholar
  16. 16.
    L. H. Smith, in: “Contemporary Issues in Nephrology”, Vol. 5, F. L. Coe, B. M. Brenner, and J. H. Stein, eds., Churchill Livingstone, New York (1980).Google Scholar
  17. 17.
    L. H. Smith, Personal communication.Google Scholar
  18. 18.
    A. F. Hofmann, P. J. Thomas, L. H. Smith and J. T. McCall, Gastroenterol. 58:960 (1970).Google Scholar
  19. 19.
    V. S. Chadwick, K. Modha, and R. H. Dowling, New Engl. J. Med. 289:172 (1973).PubMedCrossRefGoogle Scholar
  20. 20.
    A. F. Hofmann, M. F. Laker, K. Dharmsathaphorn, H. P. Sherr, and D. Lorenzo, Gastroenterol. 84:293 (1983).Google Scholar
  21. 21.
    H. J. Binder, Gastroenterol. 67:441 (1974).Google Scholar
  22. 22.
    D. L. Earnest, H. E. Williams, and W. H. Admirand. Trans. Assoc. Am. Physns. 88:224 (1975).Google Scholar
  23. 23.
    E. Hylander, S. Jarnum, H. J. Jensen, and M. Thale, Scand. J. Gastroenterol. 13:577 (1978).PubMedCrossRefGoogle Scholar
  24. 24.
    H. Andersson, R. Jagenburg, Gut 15:360 (1974).PubMedCrossRefGoogle Scholar
  25. 25.
    D. L. Earnest, G. Johnson, H. E. Williams, and W. H. Admirand, Gastroenterol. 66:1114 (1974).Google Scholar
  26. 26.
    E. Hylander, S. Jarnum, and K. Nielsen, Scand. J. Gastroenterol. 15:349 (1980).PubMedCrossRefGoogle Scholar
  27. 27.
    W. F. Caspary, J. Tonissen, and P. G. Lankisch, Acta Hep. Gastroenterol. 24:193 (1977).Google Scholar
  28. 28.
    R. Modigliani, D. Labayle, C. Aymes, and R. Denvil, Scand. J.Gastroenterol. 13:187 (1978).PubMedCrossRefGoogle Scholar
  29. 29.
    H. Pedersen, J. Steen, Scand. J. Gastroenterol. 14:97 (1979).CrossRefGoogle Scholar
  30. 30.
    V. A. Chadwick, E. Elias, G. D. Bell, R. J. Dowling, in: “Advances in Bile Acid Research”, S. Matern, J. Hackenschmidt, P. Back and W. Gerok, eds., Schattauer Verlag, Stuttgart (1975).Google Scholar
  31. 31.
    J. W. Dobbins and H. J. Binder, Gastroenterol. 70:1096 (1976).Google Scholar
  32. 32.
    P. D. Fairclough, T. G. Feest, U. S. Chadwick, and M. L. Clark, Gut 18:240 (1977).PubMedCrossRefGoogle Scholar
  33. 33.
    D. R. Saunders, J. Sillery, and G. B. McDonald, Gut 16:543 (1975).PubMedCrossRefGoogle Scholar
  34. 34.
    R. Davies, J. Laurenson, H. J. Binder, and J. W. Dobbins (Submitted for publication)Google Scholar
  35. 35.
    R. W. Freel, M. Hatch, D. L. Earnest, and A. M. Goldner, Am. J. Physiol 245:G816 (1983).PubMedGoogle Scholar
  36. 36.
    P. Bright-Asare and H. J. Binder, Gastroenterol. 64:81 (1973).Google Scholar
  37. 37.
    S. C. Kathpelia, M. J. Favus, and F. L. Coe, Clin. Res. 29:777A (1981).Google Scholar
  38. 38.
    R. W. Freel, M. Hatch, D. L. Earnest, A. M. Goldner, Biochim. Biophys. Acta 600:838 (1980).PubMedCrossRefGoogle Scholar
  39. 39.
    M. Hatch, R. W. Freel, A. M. Goldner, and D. L. Earnest, Gut (1984) (in press).Google Scholar
  40. 40.
    J. W. Dobbins and H. J. Binder, New Engl. J. Med. 296:298 (1977).PubMedCrossRefGoogle Scholar
  41. 41.
    D. Rudman, J. L. Dedonis, M. T. Fountain, J. B. Chandler, G. G. Gerron, G. A. Fleming, and M. H. Kutner, New Engl. J. Med. 303:657 (1980).PubMedCrossRefGoogle Scholar
  42. 42.
    D. Rudman, M. H. Kutner, S. C. Redd, W. C. Waters, G. G. Gerron, and J. Bleier, J. Clin. Endocrinol. Metab. 55:1052 (1982).PubMedCrossRefGoogle Scholar
  43. 43.
    G. Gacs and D. Baritop, Gut 18:64 (1977).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • J. W. Dobbins
    • 1
  1. 1.Dept. of Internal MedicineYale UniversityNew HavenUSA

Personalised recommendations