In Vitro Effects of Light on the Regeneration of Rhodopsin

  • Rosalie K. Crouch
Chapter

Abstract

It is now well established that damage to the retina occurs from visible light at intensity levels below thresholds for thermal burns (1–3). This damage is found to be reversible in the early stages provided the pigment epithelium is intact (4). The mechanism for producing this early reversible light damage is still unknown. This chapter summarizes our preliminary in vitro results from studies to ascertain if irradiation damage results in a structural alteration to the rod outer segments (ROS) which would effect the regeneration of the visible pigment and thus lead to a temporary breakdown in the visual response.

Keywords

Electron Spin Resonance Methylene Blue Visual Pigment Difference Absorption Spectrum Vitro Effect 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
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Copyright information

© Plenum Press, New York 1980

Authors and Affiliations

  • Rosalie K. Crouch
    • 1
  1. 1.Departments of Ophthalmology and BiochemistryMedical University of South CarolinaCharlestonUSA

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