Myoblast Transfer Therapy pp 147-158
Control of Satellite Cell Proliferation
Satellite cells are reserve stem cells of adult skeletal muscle and thus represent a potential source of myogenic cells to use in myoblast replacement therapy of neuromuscular disease. Optimal application of this strategy requires knowledge of factors that control the growth and differentiation of satellite cells. Control of satellite cell proliferation is a complex phenomenon determined by the contribution of both positive and negative factors (Fig. 1).
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