Sequence Analysis of the 3′ End (8740 Nucleotides) of BECV Genome; Comparison with Homologous MHV Nucleotide Sequence

  • Pascal Boireau
  • Nathalie Woloszyn
  • Catherine Crucière
  • Ericka Savoysky
  • Jacques Laporte
Conference paper
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 276)


Bovine enteritic Coronavirus (BECV) is one of the major pathogen of neonatal calves. The viral genome is a unique 20 Kb large RNA molecule which is polyadenylated at its 3′ end. Studies of viral mRNAs suggest that eight genes are translated (Crucière & Laporte, personnal communication) and as established for MHV1 the possibility of functional bicistronic genes cannot be excluded. BECV is made of 4 major structural proteins2,3,4, a 50 kD phosphorylated nucleocapsid N, a 180 kD peplomer glycoprotein S (present on the virions as 105 and 95 kD glycosylated subunits), a 125 kD haemagglutinin HE (made up of two disulfide bridge-linked glycosylated subunits of 65 kD) and a 28 kD transmembrane glycoprotein M. The complete amino-acid sequences of these proteins have recently been deduced from nucleotide sequences of the viral genome5,6,7,8,9.


Relative Molecular Mass Mouse Hepatitis Virus Neonatal Calf Bovine Coronavirus Consensus Nucleotide Sequence 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Pascal Boireau
    • 2
  • Nathalie Woloszyn
    • 1
  • Catherine Crucière
    • 2
  • Ericka Savoysky
    • 3
  • Jacques Laporte
    • 1
  1. 1.Station de Virologie et d’Immunologie MoléculairesI.N.R.A.,C.R.J.J.Jouy en JosasFrance
  2. 2.Laboratoire de Virologie MoléculaireL.C.R.V., C.N.E.V.A.Maisons-Alfort CedexFrance
  3. 3.Laboratoire de Microbiologie Appliquée et IndustrielleFaculté des Sciences Pharmaceutiques et BiologiquesNancyFrance

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