Molecular and Cellular Biology of Insulin-like Growth Factors and Their Receptors pp 57-71 | Cite as
Feedback Regulation of Growth Hormone Gene Expression by Insulin-like Growth Factor I
Chapter
Abstract
Growth hormone (GH) is quantitatively the main hormone secreted by the pituitary and is under hormonal control emanating from both central and peripheral sources.
Keywords
Growth Hormone Growth Hormone Gene Growth Hormone mRNA Growth Hormone Expression Growth Hormone mRNA Level
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References
- 1.Miller WL, Eberhardt NL 1983 Structure and evolution of the growth hormone gene family. Endocrinol Rev 4:97.CrossRefGoogle Scholar
- 2.Lewis VJ, Dunn JT, Bonewald LF, Seavey BK, Vanderlaan WP 1978 A naturally occuring structural variant of human growth hormone. J Biol Chem 253:2687.Google Scholar
- 3.Lewis VJ, Bonewald LF, Lewis VJ 1980 The 20,000-dalton variant of human growth hormone location of the amino acid deletions. Biochem Biophys Res Commun 92:511.PubMedCrossRefGoogle Scholar
- 4.Seeburg PH 1982 The human growth hormone gene family. Nucleotide sequences show recent divergence and predict a new polypeptide hormone DNA 1:234.Google Scholar
- 5.Frankenne F, Rentier-Delrve F, Scippo ML, Martial J, Hennen G 1987 Expression of the growth hormone variant gene in human placenta. J Clin Endocrinol Metab 64:635.PubMedCrossRefGoogle Scholar
- 6.Thorner MO, Vance ML 1988 Growth hormone. J Clin Invest 82:745.Google Scholar
- 7.Barinaga M, Yamamoto G, Rivier C et al 1983 Transcriptional regulation of growth hormone gene expression by growth hormone releasing factor. Nature 306:84.PubMedCrossRefGoogle Scholar
- 8.Barinaga M, Bilezikjian LM, Vale MW, Rosenfeld MG, Evans RM 1985 Independent effects of growth hormone releasing factor on growth hormone release and gene transcription. Nature 314:279.PubMedCrossRefGoogle Scholar
- 9.Thorner MO, Peryman RL, Cronin MJ, et al 1982 Somatotroph hyperplasia: Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor. J Clin Invest 70:965.PubMedCrossRefGoogle Scholar
- 10.Guilllemin RR, Brazeau P, Bohlen P et al 1982 Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly. Science 218:585.CrossRefGoogle Scholar
- 11.Ling N, Zeytin F, Bohlen P et al 1985 Growth hormone releasing factors. Annu Rev Biochem 54:403.PubMedCrossRefGoogle Scholar
- 12.Frohman LA, Jansson JO 1986 Growth hormone-releasing hormone. Endocr Rev 7:223.PubMedCrossRefGoogle Scholar
- 13.Brazeau P, Vale W, Burgus R et al 1973 Hypothalamic polypeptide that inhibits the secretion of immunoreactive pituitary growth hormone. Science 179:77–79.PubMedCrossRefGoogle Scholar
- 14.Takemoto K, Rokaeus A, Joruvav H, Mc Donald TJ, Mutt V 1983 Galanin-a novel biologically active peptide from porcine intestine. FEBS Lett 164:124.CrossRefGoogle Scholar
- 15.Ch’ng JLC, Christofides ND, Anand P, Gibson SJ, Allen YS, Su HC, Takemoto K 1985 Distribution of galanin immunoreactivity in the central nervous system and the responses of galanin-containing pathways to injury. Neuroscience 16:343.PubMedCrossRefGoogle Scholar
- 16.Murakami Y, Kto Y, Koshiyama H, Inove T, Yanaihara N, Imura H 1987 Galanin stimulates growth hormone (GH) secretion via GH-releasing factor (GRF) in conscious rats. Evr J Pharmacol 136:415.CrossRefGoogle Scholar
- 17.Ottlecz A, Samson WK, McCann SM 1986 Galanin: evidence for a hypothalamic site of action to release growth hormone. Peptides 7:51.PubMedCrossRefGoogle Scholar
- 18.Baver FE, Ginsburg L, Venetikov M, MacKay DJ, Burrin JM, Bloom SR 1986 Growth hormone release in man induced by galanin, a new hypothalamic peptide. Lancet 2:192.Google Scholar
- 19.Yaffe BM, Samuels HH 1984 Hormonal regulation of the growth hormone gene: Relationship of the rate of transcription to the level of nuclear thyroid hormone-receptor complexes. J Biol Chem 259:6284.PubMedGoogle Scholar
- 20.Evans RM, Birnberg NC, Rosenfeld MG 1982 Glucocorticoid and thyroid hormones transcriptionally regulate growth hormone gene expression. Proc Natl Acad Sci USA 79:7659.PubMedCrossRefGoogle Scholar
- 21.Yamashita S, Melmed S 1986 Insulin regulation of rat GH gene transcription. J Clin Invest 78:1008.PubMedCrossRefGoogle Scholar
- 22.Wehrenberg WB, Baird A, Ling N 1983 Potent interaction between glucocorticoids and growth hormone-releasing factor in vivo. Science 221:556.PubMedCrossRefGoogle Scholar
- 23.Clemmons DR, Van Wyk JJ 1984 Factors controlling blood concentrations of somatomedin-C. Clin Endocrinol Metab 13:113.PubMedCrossRefGoogle Scholar
- 24.Isgaard J, Moller C, Isaksson OGP, Nilsson F, Mathews LS, Norstedt G 1988 Regulation of insulin-like growth factor messenger ribonucleic acid in rat growth plate by growth hormone. Endocrinology 122:1515.PubMedCrossRefGoogle Scholar
- 25.Rinderknecht E, Humber RE 1978 The amino acid sequence of human insulin-like growth factor I and its structural homology with proinsulin. J Biol Chem 253:2769.PubMedGoogle Scholar
- 26.Klapper DG, Svoboda ME, Van Wyk J 1983 Sequence analysis of somatomedin-C: Confirmation of identity with insulin-like growth factor I. Endocrinology 112:2215.PubMedCrossRefGoogle Scholar
- 27.Ullrich A, Berman CH, Dulet J, Gray A, Lee JM 1984 Isolation of the human insulin-like growth factor I gene using a single synthetic DNA probe. EMBOJ 3:361.Google Scholar
- 28.Tricoli JV, Rall RB, Scott J, Bell GI, Shows TB 1984 Localization of insulin-like growth factor genes to human chromosomes 11 and 12. Nature 310:784.PubMedCrossRefGoogle Scholar
- 29.D’Ercole AJ, Stiles AD, Underwood LE 1984 Tissue concentrations of somatomedin-C: Further evidence for multiple sites of synthesis and paracrine/autocrine mechanisms of actin. Proc Natl Acad Sci USA 81:935PubMedCrossRefGoogle Scholar
- 30.Lund PK, Moats-Staats BM, Hynes MA, D’Ercole AJ, Jansen M, Van Wyk JJ 1986 Somatomedin-C/IGF-I and IGF-II mRNAs in rat fetal and adult tissues. J Biol Chem 261:14539.PubMedGoogle Scholar
- 31.Murphy LJ, Bell GI, Friesen HG 1987 Tissue distribution of insulinlike growth factor I and II messenger ribonucleic acid in the adult rat. Endocrinology 120:1279.PubMedCrossRefGoogle Scholar
- 32.Fagin JA, Pixley S, Slanina S et al 1987 Insulin-like growth factor I gene expression in GH3 rat pituitary cells: mRNA content, immunocytochemistry and secretion. Endocrinology 120:2037.PubMedCrossRefGoogle Scholar
- 33.Elgin RG, Busby WH, Clemmon DR 1987 An insulin-like growth factor (IGF) binding protein enhances the biologic response to IGF-I. Proc Natl Acad Sci USA 84:3254.PubMedCrossRefGoogle Scholar
- 34.Flier JS, Usher P, Moses AC 1986 Monoclonal antibody to the Type I insulin-like growth factor (IGF-I) receptor blocks IGF-I receptor-mediated DNA synthesis: Clarification of the mitogenic mechanism of IGF-I and insulin in human skin fibroblasts. Proc Natl Acad Sci USA 83:664.PubMedCrossRefGoogle Scholar
- 35.Conover CA, Liu F, Powell D, Rosenfeld RG, Hintz RL 1989 Insulin-like growth factor binding proteins from cultured human fibroblasts: Characterization and hormonal regulation. J Clin Invest 83:852.PubMedCrossRefGoogle Scholar
- 36.Berelowitz M, Szabo M, Frohman LA et al 1981 Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary. Science 212:1279.PubMedCrossRefGoogle Scholar
- 37.Ono M, Miki N, Miyoshi H 1985 Decreased content and release of hypothalamic GH-releasing factor in rats bearing GH producing GH3 tumors. 67th Ann Mtg of the Endo Soc, Baltimore, MD p 126 (Abstract).Google Scholar
- 38.Rosenfeld RG, Ceda G, Wilson DM et al 1984 Characterization of high affinity receptors for insulin-like growth factors I and II on rat anterior pituitary cells. Endocrinology 114:1571.PubMedCrossRefGoogle Scholar
- 39.Goodyer CG, Stephano LD, Lai WH et al 1984 Characterization of insulin-like growth factor receptors in rat anterior pituitary hypothalamus and brain. Endocrinology 114:1187.PubMedCrossRefGoogle Scholar
- 40.Rosenfeld RG, Ceda G, Cutler CW et al 1985 Insulin and insulin-like growth factor receptors on cloned rat pituitary tumor cells. Endocrinology 117:2008.CrossRefGoogle Scholar
- 41.Nagomi H, Suzuki K, Enomoto H, Ishikawa H 1989 Studies on the development of growth hormone and prolactin cells in the rat pituitary gland by in situ hybridization. Cell Tissue Res 255:23.Google Scholar
- 42.Dupouy JP, Coffingny LL, Marge S 1975 Maternal and fetal corticosterone levels during late pregnancy in rats. J Endocrinol 65:347.PubMedCrossRefGoogle Scholar
- 43.Hemming FJ, Begeot M, Dubois MP, Dubois PM 1984 Fetal rat somatotrophs in vitro: Effects of insulin, Cortisol and growth hormone-releasing factor on their differentiation: A light and electron microscopic study. Endocrinology 114:2107.PubMedCrossRefGoogle Scholar
- 44.Silverman Bl, Bettendorf M, Kaplan SL, Grumbach MM, Miller WL 1989 Regulation of growth hormone (GH) secretion by GH-releasing factor, somatostatin and insulin-like growth factor I in ovine fetal and neonatal pituitary cells in vitro. Endocrinology 124:84.PubMedCrossRefGoogle Scholar
- 45.de Zegher F, Bettendorf M, Kaplan SL, Grumbach MM 1988 Hormone ontogeny in the ovine fetus. XXI The effect of insulin-like growth factor I on fetal plasma growth hormone, insulin and glucose concentrations. Endocrinology 122:658.CrossRefGoogle Scholar
- 46.Goodyer CG, Marcovitz S, Hardy J, Lefevre Y, Guyda HJ, Posner BI 1986 Effect of insulin-like growth factors on humal fetal, adult normal and tumor pituitary function in tissue culture. Acta Endocrinol (Copenh) 112:49.Google Scholar
- 47.Macleod RM, De Witt GW, Smith MC 1966 Hormonal properties of transplanted pituitary tumors and their relation to the pituitary gland. Endocrinology 79:1149.PubMedCrossRefGoogle Scholar
- 48.Peake GT, Mariz IK, Daughaday WH 1968 Radioimmunoassay of growth hormone in rats bearing somatotropin producing tumors. Endocrinology 83:714.PubMedCrossRefGoogle Scholar
- 49.Sawano S, Arimura A, Bowers CY et al 1967 Effect of CNS depressants, dexamethasone and growth hormone on the response of growth hormone-releasing factor. Endocrinology 81:1410.PubMedCrossRefGoogle Scholar
- 50.Katz SH, Molitch ME, McCann SM 1969 Effects of hypothalamic implants of GH on anterior pituitary weight and GH concentration. Endocrinology 85:725.PubMedCrossRefGoogle Scholar
- 51.Tannenbaum GS 1980 Evidence for autoregulation of GH secretion via the central nervous system. Endocrinology 107:2117.PubMedCrossRefGoogle Scholar
- 52.Voogt JL, Clemens JA, Negro-Villar et al 1971 Pituitary GH and hypothalamic GRF after median eminence implantation of ovine or human GH. Endocrinology 88:1363.PubMedCrossRefGoogle Scholar
- 53.Sakuma M, Knobil E 1970 Inhibition of endogenous growth hormone secretion by exogenous growth hormone infusion in the rhesus monkey. Endocrinology 86:8904.Google Scholar
- 54.Abrams RL, Grumbach MM, Kaplan SL 1971 The effect of human groth hormone on plasma growth hormone, Cortisol, glucose and free fatty acid response to insulin: Evidence for growth hormone autoregulation in man. J Clin Invest 50:940.PubMedCrossRefGoogle Scholar
- 55.Mendelson WB, Jacobs LS, Gillin JC 1983 Negative feedback suppression of sleep-related growth hormone secretion. J Clin Endocrinol Metab 56:486.PubMedCrossRefGoogle Scholar
- 56.Sheppard MC, Kronheim S, Pimstone BL 1978 Stimulation by growth hormone of somatostatin release from the rat hypothalamus in vitro. Clin Endocrinol (Oxf) 9:583.CrossRefGoogle Scholar
- 57.Hoffman DL, Baker BL 1977 Effects of treatment with growth horone on somatostatin in the median eminence of hypophysectomized rats. Proc Soc Exp Biol Med 156:265.PubMedGoogle Scholar
- 58.Patel YC 1979 Growth hormone stimulates hypothalamic somatostatin. Life Sci 24:1589.PubMedCrossRefGoogle Scholar
- 59.Molitch ME, Hlivyak LE 1980 Growth hormone short-loop feedback: Anatomic specificity of growth hormone stimulation of hypothalamic somatostatin concentration. Horm Metab Res 12:559.PubMedCrossRefGoogle Scholar
- 60.Berelowitz M, Firestone SI, Frohman LA 1981 Effects of growth hormone excess and deficiency on hypothalamic somatostatin content and release and on tissue somatostatin distribution. Endocrinology 109:714.PubMedCrossRefGoogle Scholar
- 61.Chihara K, Minamitani N, Kaji H et al 1981 Intraventricularly injected growth hormone stimulates somatostatin release into rat hypophysial portal blood. Endocrinology 109:2279.PubMedCrossRefGoogle Scholar
- 62.Brazeau P, Guillemin R, Ling N et al 1982 Inhibition by somatomedins of growth hormone secretion stimulated by hypothalamic growth hormone releasing factor (somatocrinin, GRF) on the synthetic peptide hpGRF. C R Acad Sci [D] (Paris) 295:651.Google Scholar
- 63.Goodyer CC, De Stephano L, Guyda HJ et al 1984 Effects of insulinlike growth factor on adult male rat pituitary function in tissue culture. Endocrinology 115:1568.PubMedCrossRefGoogle Scholar
- 64.Yamashita S, Melmed S 1986 Insulin-like growth factor I action on rat anterior pituitary cells: Suppression of growth hormone secretion and messenger ribonucleic acid levels. Endocrinology 118:176.PubMedCrossRefGoogle Scholar
- 65.Melmed S, Yamashita S 1986 Insulin-like growth factor I action on hypothyroid rat anterior pituitary cells: Suppression of 3, 5, 3′-triiodothyronine-induced growth hormone secretion and messenger ribonucleic acid levels. Endocrinology 118:1483.PubMedCrossRefGoogle Scholar
- 66.Goodyer CG, Marcovitz S, Hardy J et al 1986 Effect of insulin-like growth factors on human foetal, adult normal and tumour pituitary function in tissue culture. Acta Endocrinolo 112:49.Google Scholar
- 67.Yamashita S, Slanina S, Kado H et al 1986 Autoregulation of pituitary growth hormone messenger RNA levels in rats bearing transplantable mammosomatotrophic pituitary tumors. Endocrinology 118:915.PubMedCrossRefGoogle Scholar
- 68.Abe H, Molitch Me, Van Wykk JJ et al 1983 Human growth hormone and somatomedin-C suppresses the spontaneous release of growth hormone in unanesthetized rats. Endocrinology 113:1319.PubMedCrossRefGoogle Scholar
- 69.Tannenbaum GS, Guyda HJ, Posner BI 1983 Insulin-like growth factors: A role in growth hormone negative feedback and body weight regulatin via brain. Science 220:77.PubMedCrossRefGoogle Scholar
- 70.Yamashita S, Melmed S 1987 Insulin-like growth factor I regulation of growth hormone gene transcription in primary rat pituitary cells. J Clin Invest 79:449.PubMedCrossRefGoogle Scholar
- 71.Yamashita S, Weiss M, Melmed S 1986 Insulin-like growth factor I regulates growth hormone secretion and messenger ribonucleic acid levels in human pituitary tumor cells. JCEM 63(3)730.PubMedGoogle Scholar
- 72.Yamashita S, Ong J, Melmed S 1987 Regulation of human growth hormone gene expression by insulin-like growth factor I in transfected cells. J Biol Chem 262:13254.PubMedGoogle Scholar
- 73.Prager D, Gebremedhin S, Melmed S 1989 Insulin-like growth factor I responsive DNA elements on the human growth hormone gene promoter, (submitted)Google Scholar
- 74.Lefevre C, Imagawa M, Dana S, Grindlay J, Bodner M, Karin M 1987 Tissue-specific expression of the human growth hormone gene is conferred in part by binding of a specific trans-acting factor. EMBO Journal 6:971.PubMedGoogle Scholar
- 75.Moore DD, Marks AR, Buckley DI, Kapler G, Payvar F, Goodman HM 1985 The first intron of the human growth hormone gene contains a binding site for glucocorticoid receptor. Proc Natl Acad Sci USA 82:699.PubMedCrossRefGoogle Scholar
- 76.Slater EP, Rabenau O, Karin M, Baxter JJ, Beatro M 1985 Glucocorticoid receptor binding and activation of a heterologous promoter by dexamethasone by the first intron of the human growth hormone gene. Mol Cell Biol 5:2984.PubMedGoogle Scholar
- 77.Prager D, Melmed S 1988 Insulin regulates expression of the human growth hormone gene in transfected cells. J Biol Chem 263(32): 16580.PubMedGoogle Scholar
- 78.Clemmons DR, Van Wyk JJ 1985 Evidence for a functional role of endogenously produced somatomedin-like peptides in the regulation of DNA synthesis in cultured human fibroblasts and porcine aortic smooth muscle cells. J Clin Invest 75:1914.PubMedCrossRefGoogle Scholar
- 79.Binoux M, Hossenlopp P, Lassarre C, Hardovin N 1981 Production of insulin like growth factors and their carrier by rat pituitary gland and brain expiants in culture. FEBS Letts 124:178.CrossRefGoogle Scholar
- 80.Fagin JA, Brown A, Melmed S 1988 Regulation of pituitary insulin like growth factor I messenger ribonucleic acid levels in rats harboring somatommamotropic tumors: Implications for growth hormone autoregulation. Endocrinology 122:2204.PubMedCrossRefGoogle Scholar
- 81.Fagin JA, Fernandez Mejia C, Melmed S 1989 Pituitary insulin like growth factor I gene expression: regulation by triiodothyronine and growth hormone. Endocrinology (in press).Google Scholar
- 82.Herington AC, Kuffer AD 1981 Identification of a specific inhibitor of non-suppressible insulin-like activity in a partially purified human serum fraction. Endocrinology 109:1634.PubMedCrossRefGoogle Scholar
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© Plenum Press, New York 1989