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Evidence for Defective Myoblasts in Duchenne Muscular Dystrophy

  • Helen M. Blau
  • Cecilia Webster
  • Grace K. Pavlath
  • Choy-Pik Chiu
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 182)

Abstract

Duchenne muscular dystrophy (DMD) is a degenerative disorder associated with progressive muscle weakness. Affected children eventually die from respiratory or cardiac failure and rarely survive to adulthood. It is a genetic disease due to a defect at a single locus on the X-chromosome and is therefore transmitted by female carriers to their sons. The disease is relatively common; one in 4,800 males or a total of approximately 20,000 boys in the United States has DMD (239).

Keywords

Creatine Kinase Satellite Cell Duchenne Muscular Dystrophy DUCHENNE Muscular Dystrophy Creatine Kinase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • Helen M. Blau
    • 1
  • Cecilia Webster
    • 1
  • Grace K. Pavlath
    • 1
  • Choy-Pik Chiu
  1. 1.Department of PharmacologyStanford University School of MedicineStanfordUSA

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